TY  - JOUR
T1  - Detection of Antimicrobial Activity of Aspergillus terreus Against Clinical Isolates of Serratia marcescens
AU  - Mohammed, Maryam Kamel
AU  - Ali, Ali Muhsin
AU  - Albaayit, Shaymaa Fadhel Abbas
PY  - 2025
DA  - August
Y2  - 2025
DO  - 10.55549/epstem.1753613
JF  - The Eurasia Proceedings of Science Technology Engineering and Mathematics
JO  - EPSTEM
PB  - ISRES Publishing
WT  - DergiPark
SN  - 2602-3199
SP  - 93
EP  - 101
VL  - 34
LA  - en
AB  - Out of a total of fifty samples, thirty-five isolates were identified as Serratia marcescens. Thesediverse clinical samples were collected over a three-month period, from October 2023 to December 2023, fromseveral hospitals in Baghdad, including Fatima Al-Zahraa Hospital, Al-Sader Hospital, Ibn Al-Balady Hospital,and Al-Imam Ali Hospital. The clinical samples primarily included urine from patients with urinary tractinfections (UTIs). All isolates were cultured on nutrient agar, MacConkey agar, and blood agar, and theiridentities were confirmed through biochemical testing and the Vitek 2 compact system. Based on phenotypicvirulence factors, the S. marcescens isolates showed varying positive patterns: 32 out of 35 (91.42%) forprotease production, 35 out of 35 (100%) for motility, 27 out of 35 (77.14%) for hemolysin production, and 22out of 35 (62.85%) for Prodigiosin pigment production. The susceptibility of the S. marcescens isolates to twocarbapenem antibiotics (Imipenem and Meropenem) was evaluated using the disk diffusion method. Thesensitivity tests revealed high resistance to both IPM and MEM, with resistance rates of 34.28% (12 isolates)and 42.85% (15 isolates), respectively. A bioactive compound extracted from Aspergillus terreus, isolated fromsoil, demonstrated significant activity against S. marcescens at varying concentrations. Many of these fungalmetabolites exhibited potent anti-disease efficacy, and se
KW  - Multidrug resistance
KW  - Carbapenem
KW  - Virulence factors
CR  - Mohammed, M.K., Ali, A.M., & Albaayit, S.F.A. (2025). Detection of antimicrobial activity of Aspergillus
terreus against clinical isolates of Serratia marcescens. The Eurasia Proceedings of Science, Technology,
Engineering and Mathematics (EPSTEM), 34, 93-101.
UR  - https://doi.org/10.55549/epstem.1753613
L1  - https://dergipark.org.tr/en/download/article-file/5102427
ER  -