@article{article_1754549, title={The Effect of Immunotherapy on Macro-Micronutrient Intake and Its Relationship with Anthropometric Measurements in Patients with Non-Small Cell Lung Cancer}, journal={Clinical and Experimental Health Sciences}, volume={15}, pages={695–704}, year={2025}, DOI={10.33808/clinexphealthsci.1754549}, author={Doğan, Dilek and Yurttagül, S. Mine and Çil, Timuçin}, keywords={ımmunotherapy, nutritional status, anthropometric measurements, non-small cell lung cancer}, abstract={Objective: This study aims to investigate the effect of immunotherapy on macro- micronutrient intake and its relationship with anthropometric measurements in patients with non-small cell lung cancer (NSCLC). Methods: The 24-hour dietary recall and anthropometric measurements were obtained from patients diagnosed with primary NSCLC receiving immunotherapy treatment at three time points (initial, 2 months, and 6 months) at Adana City Training and Research Hospital. Statistical analyses of the data were performed using SPSS v27. Results: The study included 47 individuals (M:43, F:4) with a mean age of 64.55±8.19 years; however, the data of 30 individuals (M: 28, F: 2) (due to death/progression) who were able to complete immunotherapy treatment were evaluated. As a result of immunotherapy treatment, the median values of Water (g), Carbohydrate (g), Vitamins (A, B1, B2, C, B12), Folate, Zinc, and the mean values of Energy (kcal), Protein (g), Fat (g), Fat (%), Fiber (g), Vitamin E, Potassium, Calcium, Magnesium, Phosphorus, Iron, in the interim and final measurements were found to be higher (p <.05) than the initial measurement values. The mean Protein (%) at the interim measurement was found to be statistically higher than the mean of the final and initial measurements (p <.05). The mean of the final BMI (kg/m2), Body Fat Percentage (%) and Lean Body Mass (kg) measurements was found to be statistically higher than the mean of the interim and initial measurements (p <.05). Conclusion: During the immunotherapy treatment process, macro and micronutrient intake and anthropometric measurements increased in individuals diagnosed with NSCLC.}, number={3}, publisher={Marmara University}, organization={The authors received no financial support for the research.}