TY - JOUR T1 - Current Approaches to Stroke Management in Emergency Medicine AU - Eriten, Semih PY - 2025 DA - September Y2 - 2025 JF - Anatolian Journal of Medical Sciences PB - Bilecik Seyh Edebali University WT - DergiPark SN - 3108-4915 SP - 1 EP - 10 VL - 1 IS - 1 LA - en AB - Introduction: Stroke remains one of the leading causes of mortality and morbidity globally. Recent advances in acute ischemic stroke treatment have revolutionized emergency management approaches.Materials and Methods: A comprehensive literature search was conducted across major databases for studies published between January 2019 and December 2024. The review included randomized controlled trials, systematic reviews, and international guidelines.Results: Artificial intelligence-supported imaging systems achieved 92% sensitivity and 89% specificity in large vessel occlusion detection. Current European Stroke Organization guidelines support intravenous thrombolysis within 4.5 hours, while mechanical thrombectomy benefits patients up to 24 hours. Tenecteplase shows equivalent efficacy to alteplase with improved application ease.Conclusion: Modern stroke management requires multidisciplinary, time-sensitive approaches integrating advanced imaging, evidence-based reperfusion therapies, and organized care systems. Future developments focus on AI applications, personalized strategies, and regenerative therapies. KW - Acute ischemic stroke KW - emergency management KW - thrombolysis KW - mechanical thrombectomy KW - artificial intelligence KW - stroke systems of care KW - quality metrics CR - Abilleira, S., Pérez de la Ossa, N., Jiménez, X., et al. (2019). Transfer to the local stroke center versus direct transfer to endovascular center of acute stroke patients with suspected large vessel occlusion in the Catalan territory (RACECAT). 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