@article{article_1791081, title={Comprehensive evaluation of anxiety, depression, and quality of life in cancer patients: clinical, sociodemographic, and psychosocial influences}, journal={Journal of Medicine and Palliative Care}, volume={6}, pages={575–581}, year={2025}, author={İlhan, Nurullah and Baş, Süleyman and Hopur İlhan, Ayşegül and Tanoğlu, Alpaslan}, keywords={Anxiety, depression, quality of life, cancer, psychosocial comorbidity}, abstract={Aims: It was aimed to evaluate the prevalence of anxiety and depression among cancer patients, and examine their association with quality of life (QoL). Methods: A cross-sectional study was conducted, including 750 adult cancer patients at a tertiary oncology outpatient clinic. Anxiety and depression status were measured using the Beck Anxiety Inventory (BAI) and Beck Depression Inventory (BDI), respectively, while QoL was assessed with the EORTC QLQ-C30. Sociodemographic and clinical data were collected through structured forms. Comparative, correlation, and subgroup analyses were performed, with p <0.05 considered statistically significant. Results: The prevalence of anxiety and depression was 46.5% and 42.4%, respectively, Anxiety was more common among females, widowed individuals, and those living in non-traditional arrangements, and was highest in patients with gynecological cancers. Depression showed no significant association with demographic or clinical factors. Anxiety was negatively correlated with emotional, cognitive, and social functioning, whereas depression was selectively linked to emotional functioning. Patients with comorbid anxiety–depression demonstrated the most significant impairment in emotional functioning. Conclusion: Anxiety and depression are highly prevalent in cancer patients and exert distinct but overlapping effects on QoL, with anxiety impacting multiple functional domains. Female sex, widowhood, and limited social support emerged as key risk factors, whereas cancer type, metastasis, and comorbidity had a minor influence. These findings underscore the need for universal distress screening and integrated psychosocial support in routine oncology care.}, number={5}, publisher={MediHealth Academy Yayıncılık}