@article{article_1794003, title={Subjective Sleep Impairment and Obstructive Sleep Apnea Risk in Rosacea: A Case-Control Study}, journal={Turkish Journal of Clinics and Laboratory}, volume={16}, pages={523–530}, year={2026}, DOI={10.18663/tjcl.1794003}, url={https://izlik.org/JA34WF84WY}, author={Hacınecipoğlu, Fatmanur and Uyar, Gökberk and Yılmaz, Erkin Berkay and Kartal, Pelin}, keywords={rosacea, sleep quality, obstructive sleep apnea}, abstract={Aim: Emerging evidence suggests that rosacea may be associated with sleep disorders, alongside multiple systemic comorbidities. We aimed to evaluate sleep quality and obstructive sleep apnea risk in rosacea and their relationships with dermatology-specific quality of life. Material and Methods: In this cross-sectional case-control study, adults with rosacea (n=130) and controls (n=114) completed the Pittsburgh Sleep Quality Index (PSQI), Berlin Questionnaire (BQ), and, for patients, the Dermatology Life Quality Index (DLQI). Analyses used non-parametric tests, chi-square, Spearman correlations, and backward logistic regression. Results: Rosacea participants had higher global PSQI scores than controls (mean 6.21±3.42 vs 4.87±2.70; p=0.002) and more often met the poor-sleep threshold (PSQI>5: 63.1% vs 46.5%). BQ-defined high OSA risk did not differ significantly (30.8% vs 25.4%; p=0.356). Among patients, mean DLQI was 6.86±6.06; poor sleepers reported greater impairment (7.69±6.23 vs 5.47±5.56; p=0.021). In multivariable modeling, higher BMI (adjusted OR 1.078; p=0.006) and higher PSQI (OR 1.143; p=0.004) independently predicted rosacea status. PSQI and BQ did not differ by clinical subtype or severity. Conclusion: In this study, rosacea was associated with poorer subjective sleep without a parallel increase in questionnaire-defined OSA risk versus controls. Within rosacea, worse sleep related to higher dermatologic quality-of-life burden. Sleep health and metabolic risk appear actionable in rosacea care; incorporating brief sleep assessment, weight optimization, and selective OSA screening may support holistic management.}, number={4}