TY - JOUR T1 - The effect of influenza vaccine on arterial stiffness in young healthy adults AU - Öztürk, Ümit AU - Sünbül, Murat AU - Ertürk, Baran AU - Kaya, Barış AU - Parlatan, Derya AU - Doğruyol, Ezgi AU - Acar, Zeynep Ebrar AU - Tükenmez Tigen, Elif AU - Çinçi, Ahmet Altuğ AU - Gürel, Emre AU - Sayar, Nurten AU - Ozben, Beste AU - Tigen, Kürşat PY - 2025 DA - October Y2 - 2025 DO - 10.5472/marumj.1798635 JF - Marmara Medical Journal JO - Marmara Med J PB - Marmara University WT - DergiPark SN - 1019-1941 SP - 204 EP - 208 VL - 38 IS - 3 LA - en AB - Objective: The arterial wall possesses a complex structure. Over time, arteries lose elasticity and become stiffer due to factors such asaging, chronic diseases, and increased inflammation. Pulse wave velocity (PWV) and augmentation index (AI) are widely recognizedas direct markers of arterial stiffness. Previous studies have suggested a link between seasonal influenza infection and increasedcardiovascular mortality. This study aimed to investigate the effects of influenza vaccination on arterial stiffness in healthy youngadults.Patients and Methods: The study enrolled participants who received the influenza vaccine according to the latest guidelines. Prior tovaccination, participants completed the Hospital Anxiety and Depression Scale (HADS) to assess baseline mood and anxiety levels.Arterial stiffness was measured using an oscillometric device. After a 15-day follow-up, HADS assessments and arterial stiffnessmeasurements were repeated.Results: A total of 48 participants were initially enrolled, and 33 who completed the follow-up were included in the final analysis.Statistically significant reductions were observed in systolic blood pressure (p KW - Arterial stiffness KW - PWV KW - AI KW - Influenza vaccine CR - Segers P, Rietzschel ER, Chirinos JA. How to measure arterial stiffness in humans. 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