@article{article_184279, title={Antibacterial Effect of Different Concentration of Boric acid against Enterococcus Faecalis Biofilms in Root Canal}, journal={Marmara Dental Journal}, volume={1}, pages={76–80}, year={2014}, DOI={10.12990/ MDJ.201317716}, author={Zan, Recai and Hubbezoglu, Ihsan and Ozdemır, Ali and Tunc, Tutku and Sumer, Zeynep and Alıcı, Oguzhan}, keywords={Boric acid, root canal, microorganisms}, abstract={<p>The aim of this study was to investigate the antibacterial effects of <br />different concentration of boric acid in root canals that were <br />infected with Enterococcus faecalis biofilms. 104 single-canal <br />premolar teeth were prepared and then disinfected and sterilized. <br />E.faecalis were inoculated into the root canals and kept at 37°C for <br />24 hours. The re-inoculation procedure was repeated on the first, <br />fourth, seventh and tenth days with fresh culture. The infected root <br />canals were divided into one negative (saline), one positive <br />(sodium hypochlorite) control group, and three experimental <br />groups (boric acid; 2%, 4% and 6%) (n=20). Paper points were <br />placed in root canals before and after irrigation to control and <br />evaluate the biofilm formation. Biofilms were counted on blood <br />agar plates, and the data were evaluated and statistically analyzed <br />using one-way ANOVA and Tukey’s test. There were statistically <br />significant differences among three experimental group (boric <br />acid; 2%, 4% and 6%). Although 6% concentration of boric acid <br />indicated the highest antibacterial effect, it could not exhibit the <br />same antibacterial effect as NaOCl. As a new product boric acid <br />indicated considerable bactericidal effect against E.faecalis <br />biofilms. However, the use of boric acid can be advisable with high <br />concentrations and long irrigation time for root canals disinfection. </p>}, number={2}, publisher={Marmara University}