@article{article_189594, title={Ewing s sarcoma; experience with 12 cases}, journal={Acta Orthopaedica et Traumatologica Turcica}, volume={25}, pages={210–214}, year={2006}, DOI={10.3944/aott.v25i4.1229}, author={Zulfikar, Bulent and Gedikoglu, Gunduz}, keywords={ewing s sarcoma}, abstract={Twelve patients with localized Ewing s sarcoma were treated between 1980-1990 in Istanbul Medical School, Oncology Research-Treatment Center, Our-ChildrenLeukemia Foundation, Department of Pediatric Hematology/Oncology. There were 8 boys and 4 girls, the mean age was 8.1 (range; 3-17) years. The tumors were in the femur in 3 paitents, in the humerus and rib in 2 cases each and in the tibia, radius, vertebra, clavicula and pelvis in 1 case each. Only chemotherapy (CT) was applied to 2 cases, 1 case had CT after radiotherapy. The remaining 9 cases were treated by CT and radiotherapy (during the CT). The CT protocols were VAC (n=5), VACA (n=3), IVAD (n=3), T.9 (n=1) One patient died from the main disease. Remission were achieved in 11 cases. After 5 to 94 months (mean; 22 mo.) 8 cases had relapsed (4 of them had local and remaining had distant metastases). 4 cases were not able to be followed, 3 cases were iost by additional problems (infection, cardiotoxicity). The best prognosis was achieved from Ewing’s sarcomas which initiated from long bones, less than 100 ml tumour volumes and patients less than 5 years old. There were no significant differences between chemotherapy protocols.}, number={4}, publisher={Turkish Association of Orthopaedics and Traumatology}