@article{article_190259, title={The effects of low molecular weight heparin (enoxaparin) on the microsurgical vessel repair}, journal={Acta Orthopaedica et Traumatologica Turcica}, volume={32}, pages={329–333}, year={2006}, DOI={10.3944/aott.v32i4.2270}, author={Gurbuz, Hakan and Kocabey, Yavuz and Sarikaya, Ali and Candan, Latife}, abstract={In this study, enoxiparin as a low molecular weight heparin was used to prevent thrombosis on the microsurgical vessel repair and the results were discussed in the light of the literature. The study was performed on femoral arteries of twelve rabbits. The cutting edge on the femoral arteries which was made paralel the long axis of the vessel about 1 cm was repaired with microsurgical techniques. Enoxaparin was administered 10 mg/kg peroperatively and continued the same dose once a day for 10 days. The function of repaired vessel was evaluated with muscle perfusion scintiphotography at the 10 th day and clinical observations. At the 10 th day rabbits were sacrified and the vessel was examined by histologic evolution for thrombosis and intimal hyperplasia. No functional problems for all repaired vessel were seen. No bleeding occured. Thrombosis was observed on two vessel and intimal hyperplasia on four. We concluded that enoxiparin is a useful antithrombotic agent, but not anticoagulant, for prevention to thrombosis on microsurgical vessel repair and for that reason enoxiparin can be used as a prophylactic treatment of patients undergoing reconstructive vascular surgery.}, number={4}, publisher={Turkish Association of Orthopaedics and Traumatology}