@article{article_209752, title={Relationship Between HDLc, NonHDLc/ HDLc Ratio and Gilbert’s Syndrome}, journal={Medical Science and Discovery}, volume={2}, pages={334–338}, year={2015}, DOI={10.17546/msd.27077}, author={Ozenc, Salim and Sarlak, Hakan and Iscen, Sinan}, keywords={Gilbert’s syndrome(GS), Unconjugated hyperbilirubinemia (UB), HDL cholesterol, Non-HDL-cholesterol ,NonHDLc/HDLc ratio.}, abstract={<p> <strong>Objective: </strong> We investigated the relationship between HDL-cholesterol levels that is indirect marker of ApoA-I production in liver, Non-HDL-cholesterol that is indirect marker of ApoB and GS </p> <p> <strong>Methods: </strong> HDLc, NonHDLc/ HDLc Ratio levels were investigated in subjects with GS (n=148) and compared to healthy controls (n=148). </p> <p> <strong>Results: </strong> Age and BMI distributions were similar between the two groups. </p> <p>HDLc levels were lower in GS than the healthy controls (p=0.012). However, TC, Non-HDLc, Non-HDLc/HDLc levels were higher in GS than the healthy controls (p=0.002, p=0.001, p<0.001, respectively). In correlation analysis, UB were negatively mildly correlated with HDLc (r=−0.191, p=0.001) and positively correlated with TC (r=0.436, p<0.001), Non-HDLc (r=0.511, p<0.001) and Non-HDLc/HDLc (r=0.512, p<0.001) in the whole group. </p> <p> <strong>Conclusions: </strong> The contrary of previously studies, we would like to suggest that bilirubin is a only antioxidant agent that protects from cardiovascular disease, but not physiological hypolipidemic agent. </p>}, number={6}, publisher={Zafer AKAN}