@article{article_222004, title={Phenazine Production in The Presence of Heavy Metals in Recombinant Erwinia herbicola Bearing the Hemoglobin Gene}, journal={Süleyman Demirel Üniversitesi Fen Bilimleri Enstitüsü Dergisi}, volume={17}, pages={11–16}, year={2014}, author={Kahraman, Hüseyin and Aytan, Emel and Giray Kurt, Aslı and Özcan, Duygu}, keywords={Seconder metabolism, Erwinia herbicola, phenazine pigment, Vitreoscilla hemoglobin}, abstract={In this study, from Vitreoscilla sp. recombinant strains were obtained from cloned bacterial hemoglobin (VHb) gene (vgb) Eh [pUC8:15] and its wild-type strain Erwinia herbicola phenazine production in the presence of heavy metals were investigated. Time-dependent production of phenazine in the wild bacteria not shows a significant change. In generally, at the end of 96 hours in the presence of Pb in terms of production of wild-type bacteria phenazine 2.91 μg/ml of recombinant bacteria is to produce fenazin production 9.5 μg /ml, respectively. The average phenazine highest values were 7, 8.8, 8 and 9.5 μg/ml Cd, Co, Fe and Pb for Eh [pUC8:15]. E. herbicola is 6.32, 3.33, 6.02 and 2.99 μg/ml Cd, Co, Fe and Pb, respectively. Genetic engineering vgb, may be an effective method to increase phenazine production.}, number={2}, publisher={Süleyman Demirel University}