@article{article_237878, title={Toxic epidermal necrolysis secondary to ceftriaxone use: A case report}, journal={Dicle Medical Journal}, volume={42}, year={2016}, DOI={10.5798/diclemedj.0921.2015.04.0622}, author={İçer, Mustafa and Zengin, Yılmaz and Gündüz, Ercan and Durgun, Hasan and Orak, Murat and Üstündağ, Mehmet and Güloğlu, Cahfer}, keywords={Toksik epidermal nekroliz, seftriakson, hayati tehlike}, abstract={<p>Toxic epidermal necrolysis (TEN) is a rare, life-threatening condition that is usually associated with medication use and characterized by separation of epidermis and dermis and a scalded skin appearance. A 71-year-old man presented to emergency department with fever, malaise, and hyperemic skin eruptions and bullae. Skin lesions covered more than 70% of total body surface area. Nikolsky sign was positive. He had been begun ceftriaxone for pneumonia before. TEN was considered as the initial diagnosis; the medication he used was stopped, appropriate supportive treatment was begun, and the patient was admitted to intensive care unit. He was discharged on 8th day after skin epithelization occurred. Toxic epidermal necrolysis is a highly fatal syndrome, in which early diagnosis, stopping the offensive drug, and administering appropriate supportive treatment are important components of the management. </p> <p> <strong>Key words: </strong> Toxic epidermal necrolysis, ceftriaxone, life threatening </p>}, number={4}, publisher={Dicle University}