TY - JOUR TT - A RESEARCH ON THE PRODUCTION OF SILK SERICIN POWDERS BY USING SPRAY DRYING METHOD AU - Genç, Gözde AU - Bayraktar, Oğuz AU - Başal, Güldemet PY - 2009 DA - December JF - Textile and Apparel PB - Ege University WT - DergiPark SN - 1300-3356 SP - 273 EP - 279 VL - 19 IS - 4 KW - Fonksiyonel tekstiller KW - İpek proteini KW - Serisin KW - Püskürtmeli kurutma KW - Faktoriyel dizayn N2 - Sericin protein is usually discarded as a waste in silk industry. Production of silk sericin powders, which can be incorporated into fibers used in textile industry, by spray drying method will enable value-added utilization of waste sericin. In this study aqueous sericin solutions were used as raw material for the production of dry powders using a lab-scale spray dryer. A linear regression analyses were employed, in addition to experimental design at two levels with three factors for the analysis of three responses: moisture content, particle type and agglomeration degree. The process factors were the drying air temperature (120ºC and 160ºC), the feed rate (1.25x10-4and 2.5x10-4 dm³s-¹), and the concentration of sericin solutions of 10% and 30% (w/w) fed to the spray dryer. The three responses were analyzed statistically to determine the effective parameters and it was concluded that moisture content depended on three factors--drying air temperature being the dominant parameter. Particle size and shape depended mainly on feed rate and agglomeration depended on the moisture content of the product CR - 1. Duran, K., Ozdemir, D., Namligoz, E.S., 2007, “The Enzymatic Degumming of Silk Fibers”, Tekstil ve Konfeksiyon, Vol:17 (3), pp. 211- 216. CR - 2. Zhang, Y.Q., 2002, “Application of Natural Silk Sericin Protein in Biomaterials”, Biotechnol. Adv., vol. 20, pp. 91-100. CR - 3. Wu, J.H., Wang, Z., Xu, S.Y., 2007, “Preparation and Characterization of Sericin Powder Extracted from Silk Industry Wastewater” Food Chemistry, vol 103, pp. 1255-1262. CR - 4. Vaithanomsat, P., Kitpreechavanich, V., 2008, “Sericin Separation from Silk Degumming Wastewater”, Separation and Purification Technology, vol.59, pp. 129-133. CR - 5. Capar, G. Aygun, S. S., Gecit, M. R., 2008, “Treatment of Silk Production Wastewaters by Membrane Processes for Sericin Recovery”, Journal of Membrane Science, vol. 325, pp. 920-931. CR - 6. Fabiani, C., Pizzichini, M., Spadoni M. et al., 1996, “Treatment of Waste Water from Silk Degumming Process for Protein Recovery and Water Reuse”, Desalination, vol. 105, pp.1-9. CR - 7. Altman, G.H. Diaz, F., Jakuba, C. et al., 2003, “Silk-based Biomaterials”, Biomaterials, vol. 24, pp. 401-416. CR - 8. Jin, H.J., Chen, J., Karageorgiou, V. et al., 2004, “Human Bone Marrow Stromal Cell Responses on Electrospun Silk Fibroin Mats”, Biomaterials, vol. 25, pp. 1039-1047. CR - 9. Sarovat S, Sudatis B, Meesilpa P. et al., 2003, “The Use of Sericin as Antioxidant and Antimicrobial For Poluted Air Treatment”, Rev. Adv. Mater. Sci., vol. 5,193-198. CR - 10. Tamada, Y., 1997, “Anticoagulant and Its Production”, Japan Patent 09-227402A. CR - 11. Sasaki, M., Kato, N., Watanabe, H. et al., 2000, “Silk Protein, Sericin, Suppresses Colon Carcinogenesis Induced by 1,2- dimethylhydrazine in Mice, Oncol. Rep., vol. 7, pp. 1049-1052. CR - 12. Sasaki, M., Watanabe, H., Kato, N., 2001, “Supplemental Silk Protein, Sericin, Suppresses Colon Tumorigenesis in 1, 2- dimethylhydrazine-treated Mice by Reducing Oxidative Stress and Cell Proliferation, Biosci. Biotech. Biochem., vol. 65, pp. 2181-2186. CR - 13. Kato, N., Sato, S., Yamanaka, A. et al., 1998, “Silk Protein, Sericin, Inhibits Lipid Peroxidation and Tyrosinase Activity, Biosci. Biotech. Biochem., vol. 62, pp. 145-147. CR - 14. Kongdee, A., Bechtold T. and Teufel, L., 2005, “Modification of Cellulose Fiber with Silk Sericin”, J. Appl. Polym. Sci., vol. 96, pp. 1421- 1428. CR - 15. Kongdee, A., Okubayashi, S., Tabata, I. et al., 2007, “Impregnation of Silk Sericin into Polyester Fibers Using Supercritical Carbon Dioxide”, J. Appl. Polym. Sci., vol. 105, pp. 2091-2097. CR - 16. Gao, Y., Cranston, R., 2008, “Recent Advances in Antimicrobial Treatments of Textiles”, Textile Research Journal, vol. 78, pp. 60-72. CR - 17. Sehnal, F., 2008, “Prospects of the Practical Use of Silk Sericins”, Entomological Research, vol. 38, pp. S1–S8. CR - 18. Bogna, G.G., Halina, K., Mariusz, G., 2004, “Polymer Microspheres as Carriers of Antibacterial Properties of Textiles: A Preliminary Study, Fibres and Textiles in Eastern Europe, vol. 12(4), 48. CR - 19. Thiering, R., Dehghani, F., Dillow, A. et al., 2000, “The Influence of Operating Conditions on the Dense Gas Precipitation of Model Proteins”, J. Chem. Technol. Biotech., vol. 75, pp. 29-41. CR - 20. Stahl, K., Claesson, M., Lilliehorn, P. et al., 2002, “The Effect of Process Variables on the Degradation and Physical Properties of Spray Dried Insulin Intended for Inhalation, Int. J. Pharm., vol. 233, pp. 227-237. CR - 21. Irngartinger, M., Camuglia, V., Damm, M. et al., 2004, “Pulmonary Delivery of Therapeutic Peptides via Dry Powder Inhalation: Effects of Micronisation and Manufacturing, Eur. J. Pharm. Biopharm., vol. 58, pp. 7-14. CR - 22. Prinn, K.B., Costantino, H.R. and Tracy, M., 2002, “Statistical Modeling of Protein Spray Drying at the Lab Scale, AAPS Pharm. Sci. Tech., vol. 3, pp. 1-8. CR - 23. Sakagami, M, Kinoshita, W., Sakon, K. et al., 2002, “Mucoadhesive Beclomethasone Microspheres for Powder Inhalation Their Pharmacokinetics and Ppharmacodynamics Evaluation”, J. Control. Release, vol. 80, pp. 207-218. CR - 24. Asada, M., Takahashi, H., Okamoto, H. et al., 2004, “ Theophylline Particle Design Using Chitosan by the Spray Drying”, Int. J. Pharm., vol. 270, pp. 167-174. CR - 25. Lee-Desautes R, 2005, “Theory of van der Waals Forces as Applied to Particlate Materials”, Educ. Reso. for Part. Techn., 051Q-Lee, University of Kentucky. UR - https://dergipark.org.tr/en/pub/tekstilvekonfeksiyon/issue//251748 L1 - https://dergipark.org.tr/en/download/article-file/218125 ER -