@article{article_254227, title={Human Experimentation and the Relevant Ethicolegal Texts}, journal={Anatolian Clinic the Journal of Medical Sciences}, volume={21}, pages={223–234}, year={2016}, DOI={10.21673/anadoluklin.254227}, author={Ertin, Hakan and Temel, M. Kemal}, keywords={Experiments on human,The Helsinki declaration,Tuskegee syphilis experiment,Nürnberg Code,Hawaii Declaration}, abstract={<p style="text-align:justify;">Due to the human experimentation conducted in the Nazi Germany in the past, the subsequent Tuskegee syphilis and Guatemala STD studies, and the ongoing clinical pharmaceutical trials, potential harms to and exploitation of human subjects have long been discussed as a serious problem. Especially during the trials held in Nuremberg regarding the human experimentation that had been conducted by Nazi scientists the important lack of an internationally binding regulatory code was recognized, and the Nuremberg Code was created and adopted by countries to fill this gap. Given the ongoing in vivo pharmaceutical trials, in vitro procedures, stem cell research, etc., more various and complicated scientific research than ever before is conducted today on humans and human cells and tissues. The main tension in the field of human experimentation is between potential harms to the human subjects and potential benefits for science and humanity. A variety of scientific and ethical codes and rules have been developed and declared both in ethical declarations and in legal regulations in order to proceed to achieve these benefits without harming the subjects. In parallel with changes in these trials and research, these texts have also been either modified or supplemented by new texts. The Helsinki Declaration, for instance, has been revised for seven times up to the present. This systematic review aims to provide a source that gathers these nationally and internationally binding ethicolegaltexts concerning human experimentation </p>}, number={3}, publisher={Hayat Sağlık ve Sosyal Hizmetler Vakfı}