@article{article_259881, title={Topical Approaches to Cellulite}, journal={Marmara Pharmaceutical Journal}, volume={21}, pages={54–58}, year={2016}, DOI={10.12991/marupj.259881}, author={Alğın Yapar, Evren}, keywords={Cellulite,topical applications,herbal actives,pharmaceutical delivery systems,efficacy evaluation}, abstract={<p class="MsoNormal" style="text-align:justify;">Today, topical application of
pharmacologically active chemicals  and
local application of physical, mechanical and thermal  methods are available in order to eliminate
cellulite which is  an aesthetic problem
that affects the majority of women. Many 
products on natural or synthetic originated anti-cellulite active  ingredients have been developed with topical
application studies  performed on
cellulite developed parts. Formulations developed  against cellulite are usually in the form of
gel, emulsion, cream,  lotion or foam. In
recent years the use of pharmaceutical  delivery
systems have become important in order to increase the  penetration into the skin, to provide access
to layers, to show  activity, to regulate
the release, to enhance the stability and 
to reduce the adverse effects of the active ingredients in these  formulations. The use of liposomes,
phytosomes, ethosomes and  nanosomes
which are the vesicular carriers of the carrier systems  has drawn attention in both researches and
existing products.  Methods for measuring
the performance of anti-cellulite  products
and efficacy evaluation for research and development  of existing products are available with
non-invasive device  tool analysis. The
use of anti-cellulite topical formulations has 
become widespread with cost advantages and it is expected that  these formulations will develop and become
diversified and  spread more with both
scientific and technological progress.   </p> <p> </p>}, number={1}, publisher={Marmara University}