TY  - JOUR
TT  - Validity of platelet indices in predicting the risk of developing preeclampsia
AU  - Kurtoglu, Emel
AU  - Kokcu, Arif
AU  - Celık, Handan
AU  - Bıldırcın, Fatma Devran
AU  - Tosun, Migraci
AU  - Alper, Tayfun
AU  - Malatyalıoglu, Erdal
PY  - 2016
DA  - June
JF  - Deneysel ve Klinik Tıp Dergisi
JO  - J. Exp. Clin. Med.
PB  - Ondokuz Mayıs University
WT  - DergiPark
SN  - 1309-4483
SP  - 0
EP  - 0
VL  - 33
IS  - 2
KW  - Mean platelet volume
KW  - platelet indices; preeclampsia; pregnancy
N2  - The aim of this study was to evaluate the validity of platelet count (PC) andindices, including mean platelet volume (MPV), platelet distribution width(PDW) and platelet crit (PCT), in identifying the pregnancies at risk forpreeclampsia. Demographic data and laboratory tests for PC, MPV, PDW andPCT of 250 pregnant women (100 normotensive pregnants, 121 pregnantswith severe preeclampsia and 29 pregnants with mild preeclampsia) wereretrospectively analyzed. Platelet counts and indices were compared betweenthe study groups. MPV and PDW were significantly higher in preeclampticpregnant women when compared to the normal group (p=0.006, p=0.046) andarea under ROC curve for MPV was found statistically significant. PC, MPVand PCT were found significantly increased in late-onset preeclampsia (p<0.05)whereas there was no significant difference in these three indices in terms ofseverity of the disease. ROC analysis for MPV levels to differentiate earlyonsetand late-onset preeclamptic cases was also found statistically significant.Measurement of MPV may contribute to identify the pregnants at risk forpreeclampsia and assess the onset-time. PDW may be also useful in detection ofthe pregnant at risk for preeclampsia.
UR  - https://dergipark.org.tr/en/pub/omujecm/issue//261717
L1  - https://dergipark.org.tr/en/download/article-file/228218
ER  -