TY  - JOUR
TT  - An incidence of acute nitrate-nitrite poisoning in a Guinea pig (Cavia porcellus) colony
AU  - Rajesh, Nakulan Valsala
AU  - Kumar, Veluchamy
AU  - Ganapathi, Palanisamy
AU  - Thangapandiyan, Marudhai
PY  - 2013
DA  - June
JF  - Eurasian Journal of Veterinary Sciences
JO  - Eurasian J Vet Sci
PB  - Selcuk University
WT  - DergiPark
SN  - 1309-6958
SP  - 106
EP  - 109
VL  - 29
IS  - 2
KW  - Nitrat-nitrit zehirlenmesi
KW  - Cichorium intybus
KW  - kobay
N2  - We present an incidence of acute nitrate-nitrite poisoning ina guinea pig (Cavia porcellus) colony which resulted in thesubstantial and spontaneous death of 28 out of 88 guinea pigs.The cause of death was traced to nitrate-nitrite toxicity fromingestion of the green leaves of overfertilized Cichorium intybus.The predominant symptoms in the 28 guinea pigs were chocolatebrown bloody discharge from all natural orifices, cyanoticmucous membrane, mydriasis, and bloated abdomen. Necropsyof all the 28 animals showed hemorrhage in all visceral organsgrossly, and tubular nephrosis of the kidney, lymphoid depletionin the spleen, hydropic changes and necrosis in hepatocytes,and hemorrhages in the intestine and lungs histopathologically.Nitrate-nitrite toxicity was confirmed spectrophotometrically.The toxicological analysis of the feed samples of C. intybusrevealed 2.1 g% nitrate, 1.0 g% nitrite, and 80 ppb citrinin. Theintestinal loop had 10 ppm of nitrate and 1 ppm of nitrite. To thebest of our knowledge, this is the first report of acute nitratenitritepoisoning in guinea pigs owing to the ingestion of thegreen leaves of overfertilized C. intybus.
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UR  - https://dergipark.org.tr/en/pub/eurasianjvetsci/issue//262081
L1  - https://dergipark.org.tr/en/download/article-file/228602
ER  -