@article{article_266126, title={Metabolic and hemodynamic effects of unilateral tourniquet application on lower extremities of the patients with coronary artery disease}, journal={Marmara Medical Journal}, volume={10}, pages={91–99}, year={1997}, author={Erol, U. and Ay, B. and Doğu, D.}, keywords={Tourniquet,Coronary artery disease,Blood gas values,ECG}, abstract={<p>Objective: The aim of this study is to investigate the metabolic and hemodynamic effects of unilateral tourniquet application on lower extremities. </p> <p>Methods: Ten of the 20 patients had coronary artery disease and the remaining 10 patients without coronary artery disease were regarded as controls. The anesthesia was the same for both groups. </p> <p>Hemodynamic (SAP, DAP, MAP, HR, CVP), metabolic (K, CPK, CPK-MB, SGOT, LDH1, WBC), ETC02, Sp02, body temperature, blood gas value and ECG changes were recorded. </p> <p>Results: SAP, DAP and MAP significantly decreased in the patients with coronary artery disease after removal of the tourniquet when compared to the measurements obtained during the application (p<0.05). HR was not found to be significantly changed in the patients with coronary artery disease (p>0.05). In the control group, HR decreased during the application and significantly increased after removal of the tourniquet (p<0.05). </p> <p>A decrease in pH value and an increase in PC02 and ETC02 values were observed in both groups immediately and ten minutes after the removal of the tourniquet (p<0.05). K, CPK, LDH1, SGOT, WBC were not found to be significantly changed in both groups (p>0.05). CPK-MB increased in both groups (p<0.05). </p> <p>Conclusion: Data obtained revealed that tourniquet application may cause hemodynamic and metabolic changes and monitorization is necessary particularly in the patients with coronary artery disease. </p>}, number={2}, publisher={Marmara University}