TY - JOUR TT - Hepatocellular Carcinoma in a Dog AU - Sarıtaş, Zülfikar Kadir AU - Bozkurt, M Fatih AU - Korkmaz, Musa AU - Başer, F.Durmuş AU - Civelek, Turan PY - 2014 DA - December Y2 - 2014 JF - Erciyes Üniversitesi Veteriner Fakültesi Dergisi JO - Erciyes Üniv Vet Fak Derg PB - Erciyes University WT - DergiPark SN - 1304-7280 SP - 221 EP - 225 VL - 11 IS - 3 KW - Biyokimyasal analiz KW - hepatosellüler karsinom KW - köpek KW - ultrasonografi N2 - A female Terrier dog with the age of 11 was brought to our hospital with complains of anorexia, loss ofweight, lethargy and abdominal swelling. In the abdominal palpation, a mass extending towards the caudal in the rightquadrant was identified. Presence of a mass was confirmed in the direct radiographic examination, which supports theclinical finding. In the abdominal ultrasonography it was determined that the liver had lost its homogenous structure,there was free fluid in the abdomen, and the liver borders were irregular. The ALP, total protein, ALB and GGT wereidentified as 328 IU/L, 2.74 g/dl, 1.85 g/dl and 12.2 U/I respectively in the biochemical analysis. Experimentallaparotomy was applied to the case and a diffused mass was identified in the liver. Samples were taken from theneoplastic masses during the operation and the abdomen was closed after identifying diffused neoplastic formations inall lobes. Following the histo-pathological examination of the sample, the patient was diagnosed with hepatocellularcarcinoma. In this paper, it was aimed to report the clinical, radiological, ultrasonographic, biochemical andhaematological findings of a hepatocellular carcinoma observed in a dog. CR - 1. Cuccovillo A, Lamb CR. Cellular features of sonographic target lesions of the liver and spleen in 21 dogs and a cat. Vet Radiol Ultrasound 2001; 43(3): 275-8. CR - 2. Fukui Y, Sato J, Sato R, Yasuda J, Naito Y. Canine serum thermostable alkaline phosphatase isoenzyme from a dog with hepatocellular carcinoma. J Vet Med Sci 2006; 68 (10): 1129-32. CR - 3. Lodi M, Chinosi S, Faverzani S, Ferro E. Clinical and ultrasonographic features of canine hepatocellular carcinoma (CHC). Vet Res Commun 2007; 31 (Suppl 1): 293-5. CR - 4. Seki M, Asano K, Ishikagi K, Iida G, Watari T. En block resection of a large hepatocellular carcinoma involving the caudal vena cava in a dog. J Vet Med Sci 2011; 73(5): 693-6. CR - 5. Yamada T, Megumi F, Kitao S, Ashida Y, Nishizono K, Tsuchiya R, Shida T, Kobayashi K. Serum alpha-fetoprotein Values in Dogs with Various Hepatic Diseases. J.Vet.Med.Sci, 1999; 61(6): 657-9. CR - 6. Yener Z, Keleş İ, Karaca M. Bir van kedisinde hepatosellüler karsinom. Vet Bil Derg 2001; 17 (2): 57-63. UR - https://dergipark.org.tr/en/pub/ercivet/issue//285970 L1 - https://dergipark.org.tr/en/download/article-file/268546 ER -