TY  - JOUR
TT  - A study on piperine, active compound of black pepper
AU  - Gökalp, Faik
PY  - 2016
DA  - October
DO  - 10.21541/apjes.66230
JF  - Academic Platform - Journal of Engineering and Science
JO  - APJES
PB  - Akademik Perspektif Derneği
WT  - DergiPark
SN  - 2147-4575
SP  - 0
EP  - 0
VL  - 4
IS  - 3
N2  - Piperine, the most important compound of black pepper, is used for treating several diseases such as breast, colon, rectal, and stomach cancer. In this study, the thermodynamical properties of this molecule in blood were obtained by using DFT and HF at the level of B3LYP/6-31+g(d,p). The results of calculations indicate that Piperine is less stable. So, ıt can react easily with radicalic forms and decrease their harmful effects and damage to the cell structures. It can dissolves in blood and reaches every tissues of the body because of the high polarity.
UR  - https://doi.org/10.21541/apjes.66230
L1  - https://dergipark.org.tr/en/download/article-file/270504
ER  -