TY - JOUR TT - Determining of Gastroparesis Disease from Electrogastrogram Signals Using Cramer-Rao Lower Bound and Power Spectral Density AU - Altıntop, Çiğdem Gülüzar AU - Latifoğlu, Fatma AU - Çelikzencir, Emre AU - Can Sezgin, Gülten AU - Yurci, Mustafa Alper PY - 2017 DA - March JF - IU-Journal of Electrical & Electronics Engineering PB - İstanbul University-Cerrahpasa WT - DergiPark SN - 1303-0914 SP - 3065 EP - 3073 VL - 17 IS - 1 KW - Gastroparesis KW - Electrogastrogram KW - Cramer-Rao Lower Bound KW - Autoregressive Parameter KW - Power Spectral Density N2 - Gastroparesis is a chronic disease of stomachmobility, defined as delay in the emptying of food from the stomach withoutmechanical obstruction. Various methods are used for the diagnosisof gastroparesis and scintigraphy method is accepted as the gold standard. Inthis study, Electrogastrogram (EGG) signals were obtained from gastroparesispatients and healthy volunteers using cutaneous electrodes. Unlike the methodsused in the frequency analysis of EGG signals in the literature, parametricmethods have been used in this study and the selection of the method to be usedhas not been determined intuitively, it has been determined by mathematicalcalculations. Cramer-Rao Lower Bound (CRLB) method has been used to determinewhich method should be used for obtaining Power Spectral Density (PSD). Using selectedparameter estimation method, PSD graphs were obtained. Several features were extractedfrom the PSD graphs and they were utilized to differentiate patient and healthygroups. Asa result, features that can classify EGG signals from gastroparesis patientsand healthy subjects, have been obtained. Best electrode placement that can beused for this disease has been achieved succesfully. CR - [1] R.M. Stern, K.L. Koch, W.R. Stewart, MW. Vasey, “Electrogastrography: current issues in validation and methodology”, Psychophysiology, vol. 24, pp. 55–64, 1987. CR - [2] R.D. Rothstein, A. Alavi, J.C. Reynolds, “Electrogastrography in patients with gastroparesis and effect of longterm cisapride”, Digestive Diseases and Sciences, vol. 38, pp.1518-1524, 1993. CR - [3] J.D. Chen, Z. Lin, J. Pan, R.W. McCallum, “Abnormal gastric myoelectrical activity and delayed gastric emptying in patients with symptoms suggestive of gastroparesis”, Digestive Diseases and Sciences, vol. 41, no. 8, pp. 1538-1545,1996. UR - https://dergipark.org.tr/en/pub/iujeee/issue//288792 L1 - https://dergipark.org.tr/en/download/article-file/271979 ER -