@article{article_313546, title={Protective Effects of Bitter Almond Kernel Extract on Liver and Kidney Tissues in Streptozotocin-Induced Diabetic Rats}, journal={Turkish Journal of Science and Technology}, volume={10}, pages={31–42}, year={2015}, author={Demır, E. and Keser, S. and Yılmaz, Ö.}, keywords={Diabetes, bitter almond, malondialdehyde, glutathione, cholesterol, fatty acids}, abstract={The bitter almond has been used for a long time by diabetes patients due to some important anti-diabetic effects. In this study, we aimed to determine protective effects of bitter almond extract on the lipid-soluble vitamins, cholesterol, glutathione (GSH), total protein, malondialdehyde (MDA), fatty acid levels of liver and kidney tissues of streptozotocin-induced diabetic rats. According to our findings, in kidney tissue, GSH and total protein were decreased in the Diabetes (D) and Diabetes + Bitter Almond (D+A) groups. Again MDA was increased in the D group, but not changed in the D+A group. Our results indicated that bitter almond extract might have a positively effect on postprandial blood glucose levels, as well as, on the GSH and MDA levels in the kidney tissue. The decrease of postprandial glucose level and these positive results can be attributed to bitter almond extract in the kidney tissue. The bitter almond and streptozotocin (STZ) administrations affected amount of some important fatty acids in the liver and kidney tissues, which substrates in fatty acid metabolism on duty enzymes.}, number={1}, publisher={Fırat University}