TY - JOUR TT - Endocrine effects of pesticides AU - Demir, Sevim Sibel AU - Akçalı, Nazan AU - Akbaba, Muhsin PY - 2017 DA - February JF - The Turkish Journal Of Occupational / Environmental Medicine and Safety JO - turjoem PB - Engin TUTKUN WT - DergiPark SN - 2149-4711 SP - 21 EP - 21 VL - Volume 2 IS - Issue 1(2) KW - Endocrine effects of pesticides N2 - Commonhousehold products –detergents, disinfectants, plastics, and pesticides–containchemical ingredients that enter our bodies, disrupt hormones and cause adversedevelopmental, disease, and reproductive problems. Known as endocrinedisruptors, these chemicals, which interact with the endocrine system, wreakhavoc in humans and wildlife. Endocrine Disruptors (EDs) are defined by WHO asexogenous compounds or mixtures that alter function(s) of the endocrine systemand consequently cause adverse effects in an intact organism, or its progeny,or (sub)populations. Endocrine disruptors have been linked to attention deficithyperactivity disorder (ADHD), Parkinsons, Alzheimers, diabetes, cardiovasculardisease, obesity, early puberty, infertility and other reproductive disorders,and childhood and adult cancers. Many pesticides are now suspected of beingendocrine disruptors - chemicals that can lead to an increase in birth defects,sexual abnormalities and reproductive failure. EDCs have been suspected to beassociated with altered reproductive function in males and females; increasedincidence of breast cancer. Reproductive specialists attribute a worldwidesperm count decline by approximately 50%. The onset of puberty in girls,shifting the mean from 11.2 years to 8.9 years for African Americans and 10.0years for Caucasian girls, is linked to chemical exposure that stimulates sexhormones. Scientists believe that neurological disorders observed in children,such as ADHD and autism, may be related to the prenatal chemical disruption ofthe thyroid system. Certain pesticides are believed to alter thyroid function,interfere with brain development and cause deficits in cognitive functions inthe developing fetus. Other effects include physical and mental retardation,alterations of the cardiovascular system and musculoskeletal defects,alterations of the menstrual cycle, obesity, and failure to develop secondarysex characteristics.    Keywords: pesticide, endocrine effects, Endocrine Disruptors CR - Sevim Sibel Demir, Nazan Akçalı, Muhsin Akbaba Osmaniye Public Health Directorate Adana Public Health Directorate Çukurova University Faculty of Medicine, Department of Public Health UR - https://dergipark.org.tr/en/pub/turjoem/issue//319434 L1 - https://dergipark.org.tr/en/download/article-file/311421 ER -