@article{article_339882, title={Toxoplasma gondii seropositivity in pregnancies with normal delivery and complicated with abortion}, journal={The European Research Journal}, volume={4}, pages={275–279}, year={2018}, DOI={10.18621/eurj.339882}, author={Dinçgez Çakmak, Burcu and Dündar, Betül and Bayram, Feyza and Özgen, Gülten}, keywords={Abortus,pregnancy,toxoplasmosis,toxoplasma immunglobuline}, abstract={<p class="MsoNormal" style="text-align:justify;line-height:200%;"> <b> <span style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-us" lang="en-us">Objective: </span> </b> <span style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-us" lang="en-us"> </span> <i> <span style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-us" lang="en-us">Toxoplasma </span> </i> <span style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-us" lang="en-us"> infection during pregnancy may cause remarkable
mortality and morbidityin fetus due to transplacental transmission. It has
fetal consequences such as abortion, stillbirth and congenital malformations.
In the Turkish literature, there is limited investigations evaluating the
prevalence of <i>Toxoplasma gondii </i>among
pregnancies complicated with abortion. The aim of this study is to compare the <i>Toxoplasma </i>seropositivity between
pregnancies with normal delivery and complicated with abortion.  </span> </p> <p class="MsoNormal" style="text-align:justify;line-height:200%;"> <span style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-us" lang="en-us"> <b> Methods: </b>This is a retrospective, single center study conducted between May 2015 and
June 2016. We included 412 patients in the study group and 828 patients in the
control group. The study group (Group 1) was compromised of pregnants whose
pregnancies were complicated with abortion and the control group (Group 2) was
pregnants with normal delivery. <i>Toxoplasma </i>
IgM and IgG seropositivity were compared between two groups. </span> </p> <p class="MsoNormal" style="text-align:justify;line-height:200%;"> <span style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-us" lang="en-us"> <b>Results: </b>
There was no difference between two groups in terms of sociodemographic
features ( <i>p </i> > 0.05). <i>Toxoplasma </i> IgM was positive in 62 (5%)
patients and IgG was positive in 282 (22.9%) patients in all groups. In
subgroup analysis <i>Toxoplasma </i> IgM was
found to be positive in 27 (6.6%) patients in Group 1 and 35 (4.2%) patients in
Group 2. Moreover, <i>Toxoplasma </i> IgG was
positive in 125 (30.6%) patients in Group 1 and in 157 (19.2%) patients in
Group 2. <i>Toxoplasma </i> IgM and <i>Toxoplasma </i> IgG were significantly higher
in Group 1 ( <i>p </i> = 0.023 and <i>p </i> = 0.016, respectively).  </span> </p> <p class="MsoNormal" style="text-align:justify;line-height:200%;"> <span style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-us" lang="en-us"> <b>Conclusion: </b>
We concluded that <i>Toxoplasma </i>
seropositivity is high in our country and routine screening is essential for
pregnancies. Toxoplasmosis may play a role in the etiology of abortion.  </span> </p> <p> </p>}, number={4}, publisher={Prusa Medical Publishing}