TY - JOUR T1 - Chemotherapy application on a cat with lymphoblastic lymphosarcoma AU - Borku, Mehmet Kazim AU - Kara, Erdal AU - Kurtdede, Arif AU - Radgohar, Ayjamal AU - Kara, Halime AU - Sen, Yusuf PY - 2017 DA - December JF - Turkish Journal of Veterinary Research JO - TJVR PB - Ebubekir CEYLAN WT - DergiPark SN - 2602-3695 SP - 29 EP - 33 VL - 1 IS - 1 LA - en AB - The case was a 2.5-year-old calicocat with an abdominal mass, which was brought from a private clinic to AnkaraUniversity, Veterinary Faculty, Animal Hospital, Internal Diseases Clinic. Itwas reported that the cat was operated 20 days ago, a mass of 8 cm in diameternear the jejunum was removed, but a second mass in the region was noticed inthe investigation. The mass removed with operation was found to be Lymphoblasticlymphocarcinoma. In the ultrasonography, a two lobed mass of 3x4.5 cm in sizewas detected in the mesenterium near the liver. An alternative treatment wasconsidered to be performed instead of reoperation on determining that the massrecurred in a very short time and was malignant as a result of the pathology.Considering that the cat was young and with good general condition, it wasdecided to administer chemotherapy. Modified Wisconsin Maddison method wasselected for the chemotherapy. Shortly after the initiation of the chemotherapyprotocol, chemotherapy had to be discontinued due to dense acid accumulation inthe abdomen and deterioration of the general condition. Feline Corona Virus wasdetected positive in the cat scanned for subclinical diseases. KW - Cat KW - Lymphoblastic Lymphosarcoma KW - FIP KW - chemotherapy CR - 1- Carreas JK, Goldschmidt M, Lamb M, McLear RC, Drobatz KJ, Sorenmo KU. Feline Epitheliotropic Intestinal Malignant Lymfhoma: 10 Cases (1997-2000). J Vet Intern Med. 2013; 17(3):326-331. CR - 2- Elmslie RE, Ogilvie GK, Gilette EL, McChesney-Gilette S. Radiotherapy with and without chemotherapy for localized lymphoma ın 10 cats. Veterinary Radiology. 1991; 32(6):266-312. CR - 3- Krick EL, Moore RH, Cohen RB, Sorenmo KU. Prognostic significance of weight changes during treatment of feline lymphoma. J Fel Med Surg. 2011; 13:976-983. CR - 4- Krick EL, Cohen RB, Gregor TP, Salah PC, Sorenmo KU. Prospective Clinical Trial to Compare Vincristine and Vinblastine in a COP-Based Protocol for Lymphoma in Cats. J Vet Intern Med. 2013; 27:134-140. CR - 5- Mahony OM, Moore AS, Cotter SM. Alimentary lymphoma in cats: 28 cases (1988-1993). J Am Vet Med Assoc. 1995; 207:1593-1598. CR - 6- Mauldin GE, Mooney SC, Meleo KA. Chemotherapy in 132 cats with lymphoma (1988-1994). Vet Cancer Soc Proc. 1995; 15:35-36. CR - 7- Milner RJ, Peyton J, Cooke K, Fox LE, Gallagher A, Gordon P, Hester J. Response rates and survival times for cats with lymphoma treated with the United of Wiscconsin-Madison chemotherapy protocol: 38 cases (1996-2003). J American Vet. Med. Ass. 2005; 227(7): 1118-1122. CR - 8- Moore AS, Cotter SM, Frimberg AE. A comparison of doxorubicin and COP for maintenance of remission in cats with lymphoma. J Vet Intern Med. 1996; 10:372-375. CR - 9- Norsworthy GD, Crystal MA, Grace SF, Tilley LP. The Feline Patient, Four Edition. Chapter. 2011; 34:76-80. CR - 10- Ogilvie GK. Chemotherapy and the surgery patient: Principles and Recent Advances. Clinical Techniques in Small Practice. 1998; 13(1): 22-32. CR - 11- Reiman RA, Mauldin GE, Mauldin GN. A comparison of toxicity of two dosing schemes for doxorubicin in the cat. J Fel Med Surg. 2008; 10(4):324-331. CR - 12- Shelton GH, Grant CK, Cotter SM, Gardner MB, Hardy WD, DiGiacomo RF. Feline Immunodeficiency Virus and Feline Leukemia Virus Infections and Their Relationships to Lymphoid Malignancies in Cats: A Retrospective Study (1968-1988). J Acquired Immune Deficiency Syndromes. 1990; 3:623-630. CR - 13- Simon D, Eberle N, Laacke-Singer L, and Nolte I. Combination Chemotherapy in Feline Lymphoma: Treatment Outcome, Tolerability, and Duration in 23 Cats. J Vet Intern Med. 2008; 22:394-400. CR - 14- Stein TJ, Pellin M, Steinberg H, Chun R. Treatment of Feline Gastrointestinal Small-Cell Lymphoma with Chlorambucil and Glucocorticoids. J Am Anim Hosp Assoc. 2010; 46(6):413-417. CR - 15- Teske E, van Straten G, van Noort R and Rutteman GR. Chemotherapy with Cyclophosphamide, Vincristine, and Prednisolone (COP) in Cats with Malignant Lymphoma: New Results with an Old Protocol. J Vet Intern Med. 2002; 16(2):179-186 CR - 16- Vail DM, Moore AS, Ogilvie GK. Feline lymphoma (145 cases): Proliferation indices, cluster of differentiation 3 immunoreactivity, and their association with prognosis in 90 cats. J Vet Intern Med. 1998; 12:349-354. CR - 17- Zwahlen CH, Lucroy MD, Kraegel SA. Results of chemotherapy for cats with alimantery malignant lymphoma: 21 cases (1993-1997). J Am Vet Med Assos. 1998; 213:1144-1149. UR - https://dergipark.org.tr/en/pub/tjvr/issue//360891 L1 - https://dergipark.org.tr/en/download/article-file/384139 ER -