@article{article_364425, title={PREVALENCE AND CIRCULATING GENOTYPES OF PARVOVIRUS B19 AMONG ADULT SICKLE CELL DISEASE PATIENTS AND BLOOD DONORS IN BAHRAIN}, journal={The Eurasia Proceedings of Science Technology Engineering and Mathematics}, pages={229–235}, year={2017}, author={Sharaf, Jaleela Alawi}, keywords={Parvovirus B19,sickle cell anemia,prevalence,genotype}, abstract={ Parvovirus (PV) is a single-stranded DNA virus with a non-enveloped nucleus having a size of 18-26nm. It comprise 60 structural proteins which are of two types. PV B19 transmits through respiratory droplets or blood transfusion but some nosocomial infections also give a chance to PV B19 for causing an infection. <o:p> </o:p> <p class="MsoNormalCxSpMiddle" style="margin-bottom:0cm;margin-bottom:.0001pt; mso-add-space:auto;text-align:justify;line-height:normal;mso-pagination:none; mso-layout-grid-align:none;text-autospace:none"> <o:p>  </o:p> <p class="MsoNormalCxSpMiddle" style="margin-bottom:0cm;margin-bottom:.0001pt; mso-add-space:auto;text-align:justify;line-height:normal;mso-pagination:none; mso-layout-grid-align:none;text-autospace:none"> The study was particularly conducted on Sickle Cell Anemia (SCA) patients and focuses on the determination of parvovirus among Bahraini population by relying on their clinical status. Three groups have been taken for the serological study of PV B19. Moreover, around 100 healthy blood donors were taken in which both the males and females were included. However, samples were taken from the emergency unit of Salmania Medical Complex (SMC) and Ibrahim Khalil Kano Center (IKKC). <o:p> </o:p> <p class="MsoNormalCxSpMiddle" style="margin-bottom:0cm;margin-bottom:.0001pt; mso-add-space:auto;text-align:justify;line-height:normal;mso-pagination:none; mso-layout-grid-align:none;text-autospace:none"> <o:p>  </o:p> <p class="MsoNormalCxSpMiddle" style="margin-bottom:0cm;margin-bottom:.0001pt; mso-add-space:auto;text-align:justify;line-height:normal;mso-pagination:none; mso-layout-grid-align:none;text-autospace:none"> It is a cohort study based on total 250 people among which 150 were SCA patients, and 100 were healthy individuals. The findings reveal that approximately 40% patients suffered from VOC whereas, only 20% were detected in SCA patients with Non-Vaso-Occlusive Crises (NVOC). It was observed that the percentages were relatively same in both the male and female groups i.e. 33.2%. The percentage for the control group was 33.6 % in which 84 males and 16 females were included. <o:p> </o:p> <p class="MsoNormalCxSpMiddle" style="margin-bottom:0cm;margin-bottom:.0001pt; mso-add-space:auto;text-align:justify;line-height:normal;mso-pagination:none; mso-layout-grid-align:none;text-autospace:none"> <o:p>  </o:p> <p class="MsoNormalCxSpMiddle" style="margin-bottom:0cm;margin-bottom:.0001pt; mso-add-space:auto;text-align:justify;line-height:normal;mso-pagination:none; mso-layout-grid-align:none;text-autospace:none"> Parvovirus is a pathogenic virus and sometimes considered as life-threatening specifically for those individuals who have SCA due to which a risk of transient aplastic crisis increases. This virus is only associated with those patients who have some haematological disorders such as haemolytic anaemia and erythro-cytopenia. It is observed that just because of inappropriate features of testing the risk of PV B19 infection can increase. An effective screening test must be performed in the future to reduce the risk of PV B19 infection. <o:p> </o:p> <o:p>  </o:p> }, number={1}, publisher={ISRES Publishing}