@article{article_372022, title={FABRICATION OF ELECTROSPUN POLY (ETHYLENE TEREPHTHALATE) SCAFFOLDS: CHARACTERIZATION AND THEIR POTENTIAL ON CELL PROLIFERATION IN VITRO}, journal={Textile and Apparel}, volume={27}, pages={334–341}, year={2017}, author={Düzyer, Şebnem}, keywords={Electrospinning,polyethylene terephthalate,scaffold,cell proliferation,fibroblast,endothelial,keratinocyte}, abstract={<div style="text-align: justify; "> Fiber diameter and fiber mat porosity play a key role on cell adhesion and proliferation. Therefore, in this study, poly(ethylene  terephthalate) (PET) scaffolds consisting of fibers with different diameters and pore sizes were fabricated from solutions with different  concentrations (10, 15 and 20% wt.) by electrospinning. Also, the effect of fiber mat thickness was investigated. The scaffolds were  characterized in terms of surface and mechanical properties. The electrospun fibers had diameters ranging from 0.575 to 2.825 μm  depending on the polymer concentration. Contact angle values showed that PET scaffolds had super hydrophobic structure. After  characterization, fibroblast cells were cultured onto PET scaffolds and influence of different electrospinning parameters on cell  proliferation was discussed. Fibroblast cells showed better proliferation on scaffolds consisting of smaller diameters. After evaluation of  fibroblast cell proliferation on electrospun PET scaffolds, two different electrospun scaffolds were chosen: 1) scaffold with the smallest  fiber diameter and 2) scaffold with better mechanical properties. Endothelial and keratinocyte cells were cultured on those two  electrospun scaffolds. Cell adhesion and proliferation behavior of endothelial and keratinocyte cells on those scaffolds were  investigated. </div>}, number={4}, publisher={Ege University}