TY  - JOUR
TT  - Endocrine Disruptors and Reproductive System
AU  - Acar, Onur
AU  - Akbaba, Muhsin
AU  - Kurt, Burak
PY  - 2017
DA  - November
JF  - The Turkish Journal Of Occupational / Environmental Medicine and Safety
JO  - turjoem
PB  - Engin TUTKUN
WT  - DergiPark
SN  - 2149-4711
SP  - 12
EP  - 12
VL  - 2
IS  - 1(4)
KW  - Endocrine Disruptors and Reproductive System
N2  - Endocrinedisruptors are mixtures of exogenous substances or substances that alter thedevelopment and function of the endocrine system. These substances effect onhormone production, release, attachment, transport, activity, destruction andbody excretion.Compounds with endocrine disrupting effect can be examined in three groups.1. Synthetic endocrine disruptors are found in some products used in theindustry, agriculture and at home. Diethylstilbestrol(DES) is the most known.2. Natural endocrine disruptors do not usually cause significant side effectsbecause they are excreted in the body without accumulating in the tissues. 3. Environmental endocrine disruptors are chemicals and various environmentalpollutants developed for use in the industrial field. Enviromental pollutantsdeveloped of the mineralization of biocides, intecticides, herbicides,fungicides, industrial chemicals (bisphenol A, polyvinyl carbon ) and otherchemicals get involved in this group.The studies show that endocrine disruptors have different effect mechanisms andpathogenesis on many periods of women’s life, from puberty to menopause.(Diamanti-Kandarakis et al.,2010)Endocrine disruptors in women can lead to early/late puberty, polycystic ovarysyndrome, decreased fertility, infertility, endometriosis, early ovaryinsufficiency, uterine tumors, aneuploidia, pregnancy complications, breasttumors and endometrial tumors. (Diamanti-Kandarakis et al.,2009)The studies show that endocrine disruptors can be lead to infertility, declinein sperm quality, urogenital tumors (hypospadias, cryptorchidism) andtesticular germ cell tumors.(Sharpe and Skakkabaek et al.,2003)Many studies have shown that endocrine disruptors have health-damaging effects.Many endocrine disruptors have the ability to accumulate in our body as theycan be stored in the fat tissue. Today, it is impossible to be completelyprotect against endocrine disrupting agents. For this reason, lifestyle changesbecome important in order to minimize the effects of endocrine disruptors onour health.Adequate and balanced nutritional habits should be developed to protect againstthe effects of endocrine disruptors.  Keywords:Endocrine,Disruptors, Reproductive System 
CR  - Onur Acar, Muhsin Akbaba, Burak Kurt
Çukurova University Faculty of Medicine Department of Public Health
UR  - https://dergipark.org.tr/en/pub/turjoem/issue//383601
L1  - https://dergipark.org.tr/en/download/article-file/410766
ER  -