@article{article_391264, title={Is Perihepatic Lymphadenopaty a Prognostic Criteria for Chronic Hepatitis B?}, journal={Journal of Uludağ University Medical Faculty}, volume={31}, pages={143–145}, year={2005}, author={Özkan, Tanju Başarir and Sevinir, Betül and Bolca, Naile}, keywords={Chronic hepatitis B, Lymph node, Ultrasound}, abstract={The purpose of this study is to evaluate the change of perihepatic Iymph node size after antiviral therapy in a group of patients with chronic B hepatitis and to compare this data with serum ALT and HBV-DNA levels. Sixty two patients were studied; including 39 with chronic B hepatitis and 23 chronic HBV carrier. The presence of perihepatic lymph nodes was investigated using ultrasound before and after antiviral therapy and was compared with serum ALT and HBV-DNA levels as well as the presense of the Hbe antigen. Lymph nodes were detected in 22 patients with chronic B hepatitis and 5 chronic HBV carriers. Antiviral therapy was applied to 19 patients of whom the regression of lymph node size was found after response to the therapy (p0.05). A positive corelation between regression of lymph node size and reduction of in ALT levels in the patient group with chronic hepatitis B was detected. As a conculusion, it is suggested that the regression of the perihepatic lymph node size may be used as an indicator of success of antiviral therapy.}, number={3}, publisher={Bursa Uludağ University}