@article{article_391937, title={A Solitary Diffuse Neurofibroma with Bone Destruction}, journal={Journal of Uludağ University Medical Faculty}, volume={43}, pages={29–31}, year={2017}, url={https://izlik.org/JA44RH24DZ}, author={Aydın, Hasan Emre and Özbek, Zühtü and Arık, Deniz and Vural, Murat and Coşan, Tevfik Erhan}, keywords={Diffuse neurofibroma. Infiltration of the bone. Neurofibromatosis}, abstract={Neurofibroma is a peripheral nerve sheath tumor of neuroectodermal origin that includes Schwann cells, perineural cells and fibroblasts. Although neurofibromas are considered benign, only one case of malign transformation has been reported. Although neurofibroma is usually located in the skin and subcutaneous tissue, it has led to infiltration of the bone in our patient which is a rare condition. Surgically, total excision can be performed in the majority of solitary neurofibromas, however total excision is difficult for diffuse neurofibromas because of invasion of surrounding tissue.}, number={1}