TY - JOUR TT - DETERMINATION OF PROTOPINE IN FUMARIA DENSIFLORA DC. BY TLC- DENSITOMETRIC AND SPECTROPHOTOMETRIC METHOD AU - Fafal, Tuğçe AU - Önür, Mustafa Ali PY - 2007 DA - December DO - 10.1501/Eczfak_0000000538 JF - Journal of Faculty of Pharmacy of Ankara University JO - J. Fac. Pharm. Ankara PB - Ankara University WT - DergiPark SN - 1015-3918 SP - 223 EP - 236 VL - 36 IS - 4 KW - r: Fumaria densiflora DC. KW - Fumariaceae KW - Protopin N2 - The isoquinoline alkaloid protopine in Fumaria densiflora DC. (Fumariaceae) was quantitatively determined by TLC-densitometry and spectrophotometry. In TLC-densitometry two different solvent systems as toluene : chloroform : methanol : % 25 ammonium hydroxide (5:3:1:1) and cyclohexane : diethylamine (9:1) were used and protopine was detected as 0.351 and 0.352 % respectively. The content of protopine in Fumaria densiflora DC. was estimated as 0.366 % in spectrophotometric method. The quantitative data obtained by the use of two techniques were in good agreement UR - https://doi.org/10.1501/Eczfak_0000000538 L1 - https://dergipark.org.tr/en/download/article-file/424410 ER -