TY - JOUR TT - COLON TARGETED DRUG DELIVERY SYSTEMS AU - Türk Ceyda Tuba, Şengel AU - Hasçiçek, Canan PY - 2006 DA - June DO - 10.1501/Eczfak_0000000055 JF - Journal of Faculty of Pharmacy of Ankara University JO - J. Fac. Pharm. Ankara PB - Ankara University WT - DergiPark SN - 1015-3918 SP - 125 EP - 148 VL - 35 IS - 2 KW - Kolon KW - Kolona Yönelik İlaç Taşıyıcı Sistemler KW - Kolona Hedefleme KW - PeptitlerProteinler N2 - Colon targeted drug delivery systems have the potential to deliver drugs for the treatment of a variety of colonic diseases and to deliver proteins and peptides to the colon for their systemic absorption. In recent years, various pharmaceutical approaches have been developed for targeting the drugs to the colon include, formation of prodrugs, coating of pH-sensitive polymers, use of colon specific biodegradable polymers, time depended and pressure controlled drug delivery systems. In this review; physiology of colon and available technologies of colon targeted drug delivery systems were evaluated UR - https://doi.org/10.1501/Eczfak_0000000055 L1 - https://dergipark.org.tr/en/download/article-file/424476 ER -