TY - JOUR TT - QUANTITATION OF ACETAMINOPHEN IN PHARMACEUTICAL FORMULATIONS USING HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY AU - Süzen, Sinan AU - Akay, Cemal AU - Tartılmış, Şenol AU - Erdöl R., Serdar AU - Önal, Atilla AU - Cevheroğlu, Şemsettin PY - 1998 DA - December DO - 10.1501/Eczfak_0000000325 JF - Journal of Faculty of Pharmacy of Ankara University JO - J. Fac. Pharm. Ankara PB - Ankara University WT - DergiPark SN - 1015-3918 SP - 93 EP - 100 VL - 27 IS - 2 KW - Asetaminofen KW - parasetamol KW - yüksek basınçlı sıvı kromatografisi KW - tablet KW - şurup N2 - A reversed-phase high-performance liquid chromatographic method has heen developed for the determination of acetaminophen in pharmaceutical formulations. A C18 stationary phase is used with a methanol-water (1/2, v/v) mixture at the flow rate of 1.78 ml/min with the spectrophotometric detection at 193.3 nm. Sulphamethoxazole is used as an internal standard and analysis is completed within 5 minutes. The method showed good linearity, precision and reproducibility. The proposed method was successfully applied to the determination of acetaminophen in tablet and syrup UR - https://doi.org/10.1501/Eczfak_0000000325 L1 - https://dergipark.org.tr/en/download/article-file/424946 ER -