TY - JOUR TT - Pharmacognosic Researches on the Fruits of Boreavaorientalis Jaub. et Spach. AU - Tanker, Mekin AU - Yenen, Muallâ PY - 1978 DA - June DO - 10.1501/Eczfak_0000000244 JF - Journal of Faculty of Pharmacy of Ankara University JO - J. Fac. Pharm. Ankara PB - Ankara University WT - DergiPark SN - 1015-3918 SP - 0 EP - 0 VL - 8 IS - 1 N2 - On the fruits and seeds of Boreava orientalis Jaub. et Spach.; which is widely spread all over Anatolia, have been analyzed from morphological and anatomical standpoints. Amounts of loss on drying, ash and acid—insoluble ash, as required by codex and pharmacopeia, have been determined as 5.65 %, 2.83 % and 0.30 %, respectively. Air dried fruits and seeds of B. orientalis have been extracted with petroleum ether (b.p. 40-60°C) and a clear, yellow colored oil, at a proportion of 16.42 % has been obtained. The physical and chemical properties of this oil have been determined. These properties are: d20 = O .9221 , [ oc] 20 --F 0° .1084, n25 1 .4770; acid value 1.34, D D acidity 2.39, saponification value 184.21, ester value 182.87, iodine value 120.64, peroxide value 61.78, thiocyanogen value 81.54, hexabromide value 63.75, total fatty acids 91.33 % and unsaponifiable matter 2.09 %. In order to determine the components of the oil, methyl esters of the fatty acids have been prepared and injected to gas—liquid chro matography. The fatty acids have been determined by using a column filled with 10 % DEGS -I- 2% Epikote. However, stearic and oleic acids in this column have seen as a single peak at the same retention time and for this reason have been separated with 20 % Apiezon L column. According to the chromatograms, the follo wing fatty acids with the shown percentages are found in the oil: heptanoic (0.51 %), caprilic (0.25 %) nonanoic (0.38 %), capric (0.38 %), lauric (0.63 %), miristic (0.38 %), palmitic (6.44 %), stearic (4.41 %), oleic (23.75 %), linoleic (19.82 %), linolenic (25.63 %), arachidic (6. 82 %), and behenic (7.45 %). The unsaponifiable matter contains sterol and this has been precipitated as sterol digitonozid. By means of m.p., IR spectra and thin layer chromatography, it has been determined to be P--sitosterol. Experiments run on mice have proven that the oil has no acute or chronical toxicity. UR - https://doi.org/10.1501/Eczfak_0000000244 L1 - https://dergipark.org.tr/en/download/article-file/425422 ER -