TY - JOUR TT - LOKAL İLERİ EVRE SERVİKS KANSERİNİN TEDAVİSİNDE RADİKAL HİSTEREKTOMİ ÖNCESİ NEOADJUVANT KEMOTERAPİ AU - Çelik, Hüsnü AU - Elkıran, Tamer PY - 2008 DA - April JF - Türk Jinekolojik Onkoloji Dergisi JO - TRSGO Dergisi PB - Türk Jinekolojik Onkoloji Derneği WT - DergiPark SN - 2148-5372 SP - 25 EP - 30 VL - 11 IS - 2 KW - Lokal ileri evre serviks kanseri KW - neoadjuvant kemoterapi N2 - In early stage cervical cancer that up to stage IB1 disease and some stage IIA cancers, treatment options include surgery, radiation therapy, or both depending on the preference of the physician and patient. Treatmet of locally advanced (Stage Ib2, bulky IIA, IIb,III and IVA) cervical cancers is controversial and have no any standardization. Current treatment strategies includes primary chemoradiation, NACT, followed by radical hysterectomy and subsequent chemoradiation as indicated, and in very selected cases, primary radical hysterectomy and lymphadenectomy followed by tailored radiotherapy with concomitant chemotherapy. It was reviewed studies of primary neoadjuvant chemotherapy (NACT) followed by radical hysterectomy in this study. In Conclusiuon, NACT may be an alternative to current traetment modalities for locally advanced cervical cancer especially in developing countries. UR - https://dergipark.org.tr/en/pub/trsgo/issue//404461 L1 - https://dergipark.org.tr/en/download/article-file/439215 ER -