@article{article_405439, title={Are nasal steroids effective in children with adenoid hypertrophy?}, journal={The European Research Journal}, volume={5}, pages={311–318}, year={2019}, DOI={10.18621/eurj.405439}, author={Solmaz, Fevzi and Aşçıoğlu, Mustafa Erhan and Durgut, Osman and Dikici, Oğuzhan and Haksever, Mehmet and Akduman, Davut}, keywords={Nasal steroids,adenoid hypertrophy,flexible endoscopy,nasopharyngeal X-rays,Fujioka method}, abstract={<p class="MsoNormal" style="text-align:justify;line-height:150%;"> <b> <span style="font-size:12pt;line-height:150%;font-family:’Times New Roman’, serif;">Objectives: </span> </b> <span lang="en-us" style="font-size:12pt;line-height:150%;font-family:’Times New Roman’, serif;" xml:lang="en-us">Chronic
nasal obstruction is a common disease of childhood. Adenotonsillar hypertrophy
plays an important role in obstructive sleep apnea. The topical use of the
aerosolized forms of corticosteroids therefore seems the most appropriate route
to decrease systemic side effects. The aim of our study is to demonstrate the
effect of topical mometasone furoate especially on the adenoid volume in
patients without any allergic story. </span> </p> <p> </p> <p class="MsoNormal" style="text-align:justify;line-height:150%;"> <b> <span style="font-size:12pt;line-height:150%;font-family:’Times New Roman’, serif;">Methods: </span> </b> <span lang="en-us" style="font-size:12pt;line-height:150%;font-family:’Times New Roman’, serif;" xml:lang="en-us">The study
group consisting of 30 males and 25 females was administered topical nasal
mometasone furoate steroid treatment. The 20 patients were in the control group
where saline solution (0.9% NaCl) treatment was administered consisted of 12
males and 8 females. Nasopharyngeal X-rays before treatment revealed that 25
patients were Grade 2 and 30 patients were Grade 3 according to the Fujioka method. </span> </p> <p> </p> <p class="MsoNormal" style="text-align:justify;line-height:150%;"> <b> <span style="font-size:12pt;line-height:150%;font-family:’Times New Roman’, serif;">Results: </span> </b> <span lang="en-us" style="font-size:12pt;line-height:150%;font-family:’Times New Roman’, serif;" xml:lang="en-us">Flexible
endoscopy performed before the treatment revealed that 20 patients were Grade 2,
11 patients were Grade 3 and 24 patients were Grade 4. Nasal endoscopies
performed after 6 weeks of intranasal topical steroid therapy revealed that 45
patients were Grade 1 and 10 patients were Grade 2. A statistically significant
difference was present between endoscopic grades before and after treatment ( <i>p </i>
< 0.0001). Nasal endoscopies performed after 6 weeks in control group
receiving saline solution treatment revealed Grade 2 in 7 patients, Grade 3 in
10 patients and Grade 4 in 3 patients. There was no statistically significant
difference between in the prior and later grades of the control group ( <i>p </i>=
0.3125). </span> </p> <p> </p> <p> </p> <p class="MsoNormal" style="text-align:justify;line-height:150%;"> <b> <span lang="en-us" style="font-size:12pt;line-height:150%;font-family:’Times New Roman’, serif;" xml:lang="en-us">Conclusions: </span> </b> <span lang="en-us" style="font-size:12pt;line-height:150%;font-family:’Times New Roman’, serif;" xml:lang="en-us"> <span>We believe that the
use of intranasal steroids (mometasone furoate) for 6 weeks in patients with
pediatric chronic nasal obstruction due to adenoid hypertrophy may be an
effective treatment modality in alleviating symptoms and decreasing adenoid
volume without causing systemic side effects.  </span> </span> <b> <span lang="en-us" style="font-size:12pt;line-height:150%;font-family:’Times New Roman’, serif;" xml:lang="en-us"> </span> </b> </p> <p> <b> </b> </p> <b> </b> <p class="MsoNormal" style="text-align:justify;text-indent:35.45pt;line-height:150%;"> <span style="font-size:12pt;line-height:150%;font-family:’Times New Roman’, serif;"> </span> </p> <p> </p>}, number={2}, publisher={Prusa Medical Publishing}