TY  - JOUR
T1  - Primary leimyosarcoma of the ovary
TT  - Primer ovaryan leimyosarkom
AU  - Altunkol, Adem
AU  - Sukgen, Gökmen
PY  - 2018
DA  - December
Y2  - 2018
DO  - 10.17826/cumj.409817
JF  - Cukurova Medical Journal
JO  - Cukurova Med J
PB  - Cukurova University
WT  - DergiPark
SN  - 2602-3032
SP  - 1038
EP  - 1041
VL  - 43
IS  - 4
LA  - en
AB  - Ovarian leimyosarcoma is a rare aggressive tumor with a very bad prognosis. Contrary to their uterine counterparts, ovarian smooth muscle tumors are extremely rare comprising only 1% of ovarian tumors. Ovarian leimyosarcoma is generally seen in the postmenopausal period. Here we report a 59-year old patient diagnosed as as ovarian primary leimyosarcoma.
KW  - Ovarian neoplasm
KW  - sarcoma
KW  - leimyosarcoma
N2  - Over leimyosarkomu çok kötü prognozlu agresif nadirbir tümördür. Uterin tümörlerin aksineovaryan düz kas tümörleri, yumurtalık tümörlerinin sadece% 1'ini içeren çoknadir tümörlerdir. Ovaryan leimyosarkom genellikle postmenapozal periyottagörülür. Ancak bu vakada olduğu gibi premenapozal periyottada tanı konabilir.Primer pür ovaryan leimyosarkomlar ovaryan düz kas hücreli tümörlerin malignalt grubunu oluşturur. Bu nedenle kökenleri, etiyolojisi, histolojiközellikleri, klinik davranışları ve optimal tedavileri hala belirsizdir. 59yaşında bir hasta, karnında kitle ve ağrı şikayeti ile hastanemize başvurdu.Ameliyat öncesi çeklen abdominal ultrasonografi ve bilgisayarlı tomografide tümabdomeni dolduran kitle tespit edildi.Total histerektomi, bilateralsalpingo-ooferektomi, omentektomi, appendektomi, bilateral pelvik ve paraaortiklenf nodu diseksiyonu ve peritoneal yıkama yapıldı. Histopatolojik incelemedeprimer ovaryan leimyosarkom tespit edildi. Bildiğimiz kadarıyla mevcutvakamızla birlikte literatürde 73 vaka bildirilmiştir.
CR  - 1. Vijaya Kumar J, Khurana A, Kaur P, Chuahan AK, Singh S. A rare presentation of primary leiomyosarcoma of ovary in a young woman. Ecancermedicalscience 2015; 21; 9:524.
CR  - 2. Bouie SM, Cracchiolo B, Heller D. Epithelioid leiomyosarcoma of the ovary. Gynecol Oncol 2005; 97: 697-9.
CR  - 3. Lerwill MF, Sung R, Oliva E, Prat J, Young RH. Smooth muscle tumors of the ovary. A clinicopathologic study of 54 cases emphasizing prognostic criteria, histologic variants, and differential diagnosis. Am J Surg Pathol 2004; 28: 1436-51.
CR  - 4. He M, Deng YJ, Zhao DY, Zhang Y, Wu T. Synchronous leiomyosarcoma and fibroma in a single ovary: A case report and review of the literature. Oncol Lett 2016; 11: 2510-4.
CR  - 5. Azoury AS, Woodruff JD. Primary ovarian sarcomas: report of 43 cases from the Emil Novak Tumor Registry. Obstet Gynecol 1971; 37: 920–91.
CR  - 6. Rasmussen CC, Skilling JS, Sorosky JI, Lager DJ, Buller RE. Stage IIIC ovarian leiomyosarcoma in a premenopausal woman with multiple recurrences: prolonged survival with surgical therapy. Gynecol Oncol 1997; 66: 519-25.
CR  - 7. Piura B, Rabinovich A, Yanai-Inbar I, Glezerman M. Primary sarcoma of the ovary: report of five cases and review of the literature. Eur J Gynaecol Oncol 1998; 19: 257-61.
CR  - 8. O’Sullivan SG, Das Narla L, Ferraro E. Primary ovarian leiomyosarcoma in an adolescent following radiation for medulloblastoma. Pediatr Radiol 1998; 28: 468-70.
CR  - 9. Monk B, Nieberg R, Berek J. Primary leiomyosarcoma of the ovary in a perimenarchal female. Gynecol Oncol 1993; 48: 389-93.
CR  - 10. Young RH, Scully RE. Sarcomas metastatic to the ovary: a report of 21 cases. Int J Gynecol Pathol 1990; 9: 231-52.
CR  - 11. Friedman HD, Mazur M. Primary ovarian leiomyosarcoma. An immunohistochemical and ultrastructural study. Arch Pathol Lab Med 1991; 115: 941-5.
CR  - 12. Reddy S, Pui Poon T, Ramaswamy G, Tcherktkoff V. Leiomyosarcoma of the ovary. N Y State J Med 1985; 85: 218-20.
CR  - 13. Muntz HG, Jones MA, Goff BA, Fuller Jr AF, Nikrui N, Rice LW. Malignant mixed mullerian tumors of the ovary: experience with surgical cytoreduction and combination chemotherapy. Cancer 1995; 76: 1209-13.
CR  - 14. Barakat RR, Rubin SC, Wong G, Saigo PE, Markman M, Hoskins WJ. Mixed mesodermal tumor of the ovary: analysis of prognosis factors in 31 cases. Obstet Gynecol 1990; 80: 660-4.
CR  - 15. Nieminen U, von Numers C, Purola E. Primary sarcoma of the ovary. Acta Obstet Gynecol Scand 1969; 48: 423-32.
CR  - 16. Nasu M, Inuoe J, Matsui M, Minoura S, Matsubara O. Ovarian leiomyosarcoma:an autopsy case report. Pathol Int 2000; 50: 162-5.
CR  - 17. Nicotina PA, Antico F, Caruso C, Triolo O. Primary ovarian leiomyosarcoma. Proliferation rate and survival. Eur J Gynaecol Oncol 2004; 25: 515-6.
CR  - 18. Dai Y, Shen K, Lang JH, Huang HF, Pan LY, Wu M, et al. Primary sarcoma of the ovary: Clinicopathological characteristics, prognostic factors and evaluation of therapy. Chin Med J 2011; 124: 1316-21.
UR  - https://doi.org/10.17826/cumj.409817
L1  - https://dergipark.org.tr/en/download/article-file/475778
ER  -