@article{article_416656, title={Impact of contact lens wear on ocular surface and Meibomian glands}, journal={Ege Tıp Dergisi}, volume={57}, pages={191–194}, year={2018}, DOI={10.19161/etd.416656}, url={https://izlik.org/JA75AU99XG}, author={Barut Selver, Özlem and Palamar, Melis and Menteş, Jale and Yağcı, Ayşe}, keywords={Contact lens wear,infrared imaging,Meibomian gland,meibography,optic coherence tomography}, abstract={<p class="MsoNormal" style="margin-top:2pt;margin-right:0cm;margin-bottom:3pt;margin-left:0cm;text-align:justify;line-height:12.1pt;"> <b> <span lang="en-us" style="font-size:9pt;font-family:Arial, ’sans-serif’;" xml:lang="en-us">Aim: </span> </b> <span lang="en-us" style="font-size:9pt;font-family:Arial, ’sans-serif’;" xml:lang="en-us">To determine the impact of contact lens (CL) wear on the ocular surface and
Meibomian glands (MG). </span> <span lang="en-us" style="font-size:9pt;font-family:Arial, ’sans-serif’;" xml:lang="en-us"> </span> </p> <p> </p> <p class="MsoNormal" style="margin-top:2pt;margin-right:0cm;margin-bottom:3pt;margin-left:0cm;text-align:justify;line-height:12.1pt;"> <b> <span lang="en-us" style="font-size:9pt;font-family:Arial, ’sans-serif’;" xml:lang="en-us">Materials
and Methods: </span> </b> <span lang="en-us" style="font-size:9pt;font-family:Arial, ’sans-serif’;" xml:lang="en-us"> 24 silicone hydrogel CL wearers for a minimum
of 5 years (Group 1) and 26 healthy volunteers (Group 2) were included in this
retrospective study. Best corrected visual acuity, Oxford scoring, tear film
break-up time (T-BUT), Schirmer 1 test, Ocular Surface Disease Index (OSDI)
scoring and MG evaluation by infrared captures of optic coherence tomography
(OCT) were performed. Loss of the MG was scored blindly by a single researcher. </span> </p> <p> </p> <p class="MsoNormal" style="margin-top:2pt;margin-right:0cm;margin-bottom:3pt;margin-left:0cm;text-align:justify;line-height:12.1pt;"> <b> <span lang="en-us" style="font-size:9pt;font-family:Arial, ’sans-serif’;" xml:lang="en-us">Results: </span> </b> <span lang="en-us" style="font-size:9pt;font-family:Arial, ’sans-serif’;" xml:lang="en-us">The mean age was 30.00±6.22 in Group 1 and 28.70±4.95 in Group 2 (p=0.300).
Male/female ratio was 4/20 in Group 1 and 9/17 in Group 2. The average duration
of CL wear was 10.70±2.70 years. The mean T-BUT in Group 1 and 2 were
17.70±76.74 and 24.76±8.06 sec, respectively (p=0.002). The mean Schirmer 1
test in Group 1 and 2 were 29.04±7.67 and 25.50±8.48 mm, respectively
(p=0.129). The mean Oxford scale staining in Group 1 and 2 were 0.58±0.94 and
0.15±0.41, respectively (p=0.040). The mean OSDI scores in Group 1 and 2 were
29.36±19.25 and 23.63±21.99, respectively (p=0.334). The average upper, lower
eyelid, and total meiboscores in Group 1 and 2 were 0.95±0.87, 0.66±0.73,
1.60±1.40 and 0.67±0.59, 0.67±0.70 and 1.34±1.17, respectively. No statistical
significance was detected in any of these scores. </span> <span lang="en-us" style="font-size:10pt;font-family:Arial, ’sans-serif’;" xml:lang="en-us">  </span> </p> <p> </p> <p> </p> <p class="MsoNormal" style="margin-top:2pt;margin-right:0cm;margin-bottom:3pt;margin-left:0cm;text-align:justify;line-height:12.1pt;"> <b> <span lang="en-us" style="font-size:9pt;font-family:Arial, ’sans-serif’;" xml:lang="en-us">Conclusion: </span> </b> <span lang="en-us" style="font-size:9pt;font-family:Arial, ’sans-serif’;" xml:lang="en-us">CL wear has a variety of effects on ocular surface. MG has a significant
influence on ocular surface. Meiboscoring is an effective and practical way for
evaluation of the MG. </span> <span lang="en-us" style="font-size:10pt;font-family:Arial, ’sans-serif’;" xml:lang="en-us"> </span> </p> <p> </p>}, number={4}