TY  - JOUR
T1  - Impact of contact lens wear on ocular surface and Meibomian glands
TT  - Kontakt lens kullanımının oküler yüzey ve Meibomian bezleri üzerine etkileri
AU  - Palamar, Melis
AU  - Barut Selver, Özlem
AU  - Menteş, Jale
AU  - Yağcı, Ayşe
PY  - 2018
DA  - December
DO  - 10.19161/etd.416656
JF  - Ege Tıp Dergisi
JO  - EJM
PB  - Ege University
WT  - DergiPark
SN  - 1016-9113
SP  - 191
EP  - 194
VL  - 57
IS  - 4
LA  - en
AB  - Aim:To determine the impact of contact lens (CL) wear on the ocular surface andMeibomian glands (MG).Materialsand Methods: 24 silicone hydrogel CL wearers for a minimumof 5 years (Group 1) and 26 healthy volunteers (Group 2) were included in thisretrospective study. Best corrected visual acuity, Oxford scoring, tear filmbreak-up time (T-BUT), Schirmer 1 test, Ocular Surface Disease Index (OSDI)scoring and MG evaluation by infrared captures of optic coherence tomography(OCT) were performed. Loss of the MG was scored blindly by a single researcher.Results:The mean age was 30.00±6.22 in Group 1 and 28.70±4.95 in Group 2 (p=0.300).Male/female ratio was 4/20 in Group 1 and 9/17 in Group 2. The average durationof CL wear was 10.70±2.70 years. The mean T-BUT in Group 1 and 2 were17.70±76.74 and 24.76±8.06 sec, respectively (p=0.002). The mean Schirmer 1test in Group 1 and 2 were 29.04±7.67 and 25.50±8.48 mm, respectively(p=0.129). The mean Oxford scale staining in Group 1 and 2 were 0.58±0.94 and0.15±0.41, respectively (p=0.040). The mean OSDI scores in Group 1 and 2 were29.36±19.25 and 23.63±21.99, respectively (p=0.334). The average upper, lowereyelid, and total meiboscores in Group 1 and 2 were 0.95±0.87, 0.66±0.73,1.60±1.40 and 0.67±0.59, 0.67±0.70 and 1.34±1.17, respectively. No statisticalsignificance was detected in any of these scores.Conclusion:CL wear has a variety of effects on ocular surface. MG has a significantinfluence on ocular surface. Meiboscoring is an effective and practical way forevaluation of the MG.
KW  - Contact lens wear
KW  - infrared imaging
KW  - Meibomian gland
KW  - meibography
KW  - optic coherence tomography
N2  - Amaç: Yumuşak kontakt lens (KL)kullanımının oküler yüzey ve Meibomian bezleri üzerine etkisini araştırmak Gereçve Yöntem: Beş yılıaşkın süredir silikon hidrojel KL kullanım öyküsü bulunan 24 olgu (Grup 1) ve26 sağlıklı gönüllünün (Grup 2) en iyi düzeltilmiş görme keskinlikleri,Schirmer 1 testi, gözyaşı kırılma zamanı, oküler yüzey boyanması (Oxfordskalası), OSDI skoru ve meibomian bez özelliklerini içeren kayıtlarıretrospektif olarak değerlendirildi. Üst ve alt kapakların OCT meibografileri(Spectralis HRA+OCT; Heidelberg Engineering, Heidelberg, Germany) çekilerek bezkaybı açısından tek bir araştırmacı tarafından kör olarak değerlendirildi.Bulgular: Ortalama yaş Grup 1’de30.00±6.22, Grup 2’de ise 28.70±4.95 idi (p=0.300). Erkek/kadın oranı Grup 1’de4/20, Grup 2’de 9/17 idi. KL kullanım süresi 10.70±2.70 yıldı. Ortalama gözyaşıkırılma zamanı Grup 1’de 17.70±76.74, Grup 2’de 24.76±8.06 saniyeydi (p=0.002).Ortalama Schirmer 1 değeri Grup 1’de 29.04±7.67, Grup 2’de 25.50±8.48 mm idi(p=0.129). Oxford skalası puanı Grup 1’de 0.58±0.94, Grup 2’de 0.15±0.41 olupfark istatistiksel olarak anlamlıydı (p=0.040). OSDI skoru açısından gruplararası istatistiksel anlamlı fark bulunmamaktaydı (Grup 1: 29.36±19.25, Grup 2:23.63±21.99, p=0.334). Üst, alt kapak ve toplam meibomian bez skoru ortalamasıGrup 1’de sırasıyla 0.95 ±0.87, 0.66±0.73 ve 1.60±1.40, Grup 2’de sırasıyla0.67 ± 0.59, 0.67 ±0.70 ve 1.34±1.17 idi ve aralarındaki fark istatistikselolarak anlamlı değildi.Sonuç: Uzun süreli KL kullanımının,oküler yüzeye birçok farklı etkisi mevcuttur. Meibomian bezler, oküler yüzeyeönemli etkileri bulunan yapıladır. Meibobian bez skorlaması, Meibomian bezdeğerlendirmesi için etkili ve pratik bir yöntemdir.
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UR  - https://doi.org/10.19161/etd.416656
L1  - https://dergipark.org.tr/en/download/article-file/459895
ER  -