TY  - JOUR
T1  - A Case of Nephrotic Syndrome With Pneumocystis Jirovecii Infection
TT  - Pnömosistis Jirovecii Enfeksiyonu Tanısı Alan Nefrotik Sendrom Olgusu
AU  - Erçelik, Merve
AU  - Akın, Gül
AU  - Öneç, Kürşad
AU  - Aytekin, Fuat
AU  - Ataoğlu, Özlem
AU  - Elverişli, Mehmet Fatih
PY  - 2019
DA  - June
Y2  - 2019
DO  - 10.18521/ktd.423555
JF  - Konuralp Medical Journal
PB  - Duzce University
WT  - DergiPark
SN  - 1309-3878
SP  - 325
EP  - 328
VL  - 11
IS  - 2
LA  - en
AB  - Pneumocystis jirovecii pneumonia (commonly called Pneumocystis pneumonia or PCP) is an opportunistic infection that occurs in immunocompromised individuals. 26 year-old male patient admitted to nephrology department for hypervolemic hyponatremia and consulted to our clinic because desaturation developed. He has been diagnosed with collapsing glomerulonephritis (GN) and he was using cyclosporine and prednisolone. Postero-anterior chest X-ray showed that; left cardiodiaphragmatic sinus was blunt. In the arterial blood gas, Ph:7,42 PO2:53 mmHg PCO2:35,4 mmHg, HCO3:23,6 mEql/L. The the alveolar arterial gradient was elevated (52,75). Antibiotic and because of hypervolemia diuretic therapy was recommended to the patient. After ten days the patient's hypoxia deepened.Repeated chest X-ray showed bilateral perihilar heterogeneous opacity. Flexible bronchoscopy was performed. Pneumocystis jirovecii was detected in lavage culture. The patient treated with Trimethoprim- Sulfamethoxazole (TMP-SMZ) (3 x 7.5 mg / kg) dose. Hypoxemia improved on the 7th day of treatment and the patient was discharged. TMP-SMZ treatment was completed in 21 days. Pneumocystis developing secondary to cyclosporin toxicity Jirovecii pneumonia is a rare case.
KW  - Pneumocystis Jirovecii
KW  - Collapsing glomerulonephritis
KW  - Nephrotic syndrome
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UR  - https://doi.org/10.18521/ktd.423555
L1  - https://dergipark.org.tr/en/download/article-file/758072
ER  -