TY  - JOUR
T1  - Üç Farklı Radyoterapi Tekniği Kullanılarak Elde Edilmiş Akciğer Kanseri Tedavi Planlarının Retrospektif Olarak İncelenmesi
TT  - RETROSPECTIVE ANALYSIS OF LUNG CANCER TREATMENT PLANS OBTAINED BY USING THREE DIFFERENT RADIOTHERAPY TECHNIQUES
AU  - Bolat, Duygu
AU  - Aydın, Oğuz
AU  - Gözcü Tunç, Sema
AU  - Kıray, Zenciye
AU  - Sarıhan, Süreyya
PY  - 2018
DA  - August
Y2  - 2018
DO  - 10.32708/uutfd.424493
JF  - Journal of Uludağ University Medical Faculty
JO  - Uludağ Tıp Derg
PB  - Bursa Uludağ University
WT  - DergiPark
SN  - 1300-414X
SP  - 83
EP  - 88
VL  - 44
IS  - 2
LA  - tr
AB  - Akciğer kanserinin radyoterapi (RT) iletedavisinde; üç boyutlu konformal radyoterapi (3BKRT), yoğunluk ayarlı radyoterapi(YART) ve volümetrik ark terapi (VMAT) teknikleri kullanılarak hedef volüm ilekritik organ dozlarının karşılaştırılması amaçlanmıştır.Buçalışma için; küratif RT ile tedavi edilen 50 küçük hücreli dışı akciğerkanseri (KHDAK) tanılı hasta seçilerek, 3BKRT, YART ve VMAT tedavi planlarıoluşturuldu. Homojenite indeksi, konformite indeksi, planlama tümör volümü (PTV)ve kritik organların aldığı doz değerleri karşılaştırıldı. Tedaviplanları arasında PTV’nin Dmean (p= 0,080) değeri açısından anlamlı fark görülmedi; ancak D98%(p= 0,001)değeri VMAT tekniğinde üstün bulundu. Tüm akciğerin 5 Gy alan (V5) % değeri için (p= 0,001) VMATtekniğinin diğer tekniklere göre daha üstün olduğu görüldü. Sonuçolarak; her üç RT tekniğinde hedef volümün istenen dozu aldığı ancak; özellikleradyasyon pnömonisi gibi yan etkilerin azaltılması açısından VMAT tekniğinindaha üstün olduğu anlaşılmıştır. Teknolojik gelişmeler ışığında akciğerkanserli hastaların RT’sinde güncel tedavi yaklaşımının VMAT tekniği olduğunusöyleyebiliriz.
KW  - Akciğer kanseri
KW  - Üç Boyutlu Konformal Radyoterapi
KW  - Riskli Organ Dozları
KW  - Volümetrik Ark Terapi
KW  - Yoğunluk Ayarlı Radyoterapi
N2  - It is aimed to compare thetarget volume and critical organ doses using three dimensional conformalradiotherapy (3DCRT), intensity modulated RT (IMRT) and volumetric arc therapy(VMAT) techniques in lung cancer treated with RT. For this study; 50 patients with non-small cell lung cancer(NSCLC) who were treated with curative RT were selected and 3DCRT, IMRT andVMAT treatment plans were created. Homogeneity index, conformity index,planning tumor volume (PTV) and dose values ​​of critical organs were compared.There was no significant difference between treatment plans interms of Dmean (p = 0,080) value of PTV; but D98% (p =0.001) superior with VMAT technique. The VMAT technique was found to besuperior to the other techniques for percent volume of lung receiving more than5 Gray (V5) (p = 0.001). As a result; in all three RT techniques the target volumereceived the desired dose; it is understood that the VMAT technique is superiorin terms of reducing side effects, especially radiation pneumonia. We can saythat the current treatment approach is VMAT technique in the RT of patientswith lung cancer in the light of technological developments.
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UR  - https://doi.org/10.32708/uutfd.424493
L1  - https://dergipark.org.tr/en/download/article-file/533589
ER  -