Objective
In this study, we aimed to analyze if there is any relationship between acute renal failure, central and peripheral venous pressure measurements in adult intensive care patients.
Materials and Methods
We included 39 patients (16 F, 73.6 ± 13.9 yrs old) who were hospitalized in intensive care unit (ICU) for at least 6 days for any reason. Basal and daily creatinine values, daily systolic, diastolic, and mean blood pressures, and central venous pressure / peripheral venous pressure (CVP/PVP) measurements were recorded. Patients who had more than 50% increase in creatinine levels during follow-up were accepted as acute kidney injury (AKI, n: 12) group while patients with stable creatinine values were accepted as no-AKI (n: 27) group.
Results
Considering all patients we found that PVP and CVP measurements were positively correlated (r:.882, p: 0.0001). Mean PVP was 10.6 ± 2.4, mean CVP was 6.4 ± 2.4 and mean PVP- CVP was 4.1 ± 1.1 mmHg. A Bland-Altman diagram for the comparison between mean CVP and PVP measurements during ICU hospitalization also indicated perfect agreement (difference of-4.3). AKI and no-AKI groups were similar in means of demographic characteristics. AKI group had both higher PVP (p: 0.009) and higher CVP (0.039) values. They also had lower systolic and mean arterial pressure (p < 0.05). Patients with renal failure has the highest CVP and PVP values and lowest blood pressures compared to noAKI patients (p: 0.01).
Conclusion
We think that PVP and CVP measurements are highly correlated and both could be used as early markers for venous congestion, lower arterial filling and ARF.