TY  - JOUR
T1  - Manifestation of Ankylosing Spondylitis and Crohn`s Disease
AU  - Sulıma, Olena
AU  - Sulyma, Volodymyr
PY  - 2018
DA  - August
JF  - The Eurasia Proceedings of Science Technology Engineering and Mathematics
JO  - EPSTEM
PB  - ISRES Publishing
WT  - DergiPark
SN  - 2602-3199
SP  - 259
EP  - 261
IS  - 2
LA  - en
AB  - Regional or granulomatous ileitis is a chronicbowel disease (Crohn's disease) that covers all the layers of the intestinalwall (transmural lesions), and sometimes spreads to the mesentery, regionallymph nodes affecting both the small and large intestines, but most oftenlocalized in the terminal section of a thin guts (regional, terminal ileitis). Thesediseases can be accompanied by damage to the peripheral joints, spine, orjoints and spine. The clinical manifestations of the joint syndrome in bothprocesses are the same. The pathogenesis of the intestinal process and jointdamage has not been fully established, but it is believed that many mechanismsparticipate in it, and in particular, toxic, immune, autoimmune. In the bloodof patients, antibodies to the cells of the intestinal mucosa, lymphocytotoxinantibodies, circulating immune complexes, in which, possibly, antigeniccomponents of intestinal microbes, etc., are also present. In Crohn's disease,articular manifestations usually occur in childhood and adolescence. The developmentof peripheral arthritis in these diseases is usually not associated with thecarriage of the histocompatibility antigen B27. Ankylosing spondylitis is morecommon in men than in women (3: 1). This disease usually develops in people whohave HLA B27. Articular changes with regional ileitis occur more often inpatients with other extraintestinal manifestations of the processes - withulcers of the oral mucosa, exacerbate erythema nodosum, gangrenous pyoderma.
KW  - Ankylosing spondylitis
KW  - Crohn's disease
KW  - Manifestation
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UR  - https://dergipark.org.tr/en/pub/epstem/issue//455947
L1  - https://dergipark.org.tr/en/download/article-file/528328
ER  -