TY  - JOUR
T1  - Hipertiroidili Bir Hastada Hipokaleminin Nadir Nedeni: Gitelman Sendromu
TT  - A Rare Reason of Hypokalemia in a Hyperthyroid Patient: Gitelman Syndrome
AU  - Topaloğlu, Oya
AU  - Başer, Hüsniye
AU  - Çakır, Bekir
PY  - 2018
DA  - September
DO  - 10.17098/amj.461663
JF  - Ankara Medical Journal
JO  - Ankara Med J
PB  - Ankara Yildirim Beyazit University
WT  - DergiPark
SN  - 2148-4570
SP  - 454
EP  - 457
VL  - 18
IS  - 3
LA  - tr
AB  - Hipokalemisık görülen elektrolit bozukluklarından biridir. Azalmış potasyum alımı, hücreiçine artmış potasyum geçişi, gastrointestinal sistemden ya da üriner sistemdenartmış potasyum kaybı, ilaçlar gibi pek çok faktör hipokalemiye neden olabilir.Gitelman sendromu hipokaleminin eşlik ettiği nadir görülen otozomal resesifhastalıktır. Burada hipertiroidi nedeniyle tetkik edilirken Gitelman sendromutanısı konulan bir olguyu sunduk.
KW  - Hipokalemi
KW  - Gitelman sendromu
KW  - hipertiroidizm
N2  - Hypokalemiais one of the commonly observed electrolyte disturbances. Many factors likedecreased potassium intake, increased intracellular potassium influx, increasedexcretion from the gastrointestinal system or urinary tract, and drugs cancause hypokalemia. Gitelman syndrome is a rare autosomal recessive diseaseassociated with hypokalemia. Here, we presented a case who was examined forhyperthyroidism and finally diagnosed as Gitelman syndrome.
CR  - 1.	Monnens L, Bindels R, Grünfeld JP. Gitelman syndrome comes of age. Nephrol Dial Transplant 1998;13(7):1617-9.
CR  - 2.	Blanchard A, Bockenhauer D, Bolignano D, et al. Gitelman syndrome: consensus and guidance from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Kidney Int 2017;91(1):24-33.
CR  - 3.	Cruz DN, Simon DB, Nelson-Williams C, et al. Mutations in the Na-Cl cotransporter reduce blood pressure in humans. Hypertension 2001;37(6):1458-64.
CR  - 4.	De Jong JC, Van Der Vliet WA, Van Den Heuvel LP, Willems PH, Knoers PH, Bindels RJ. Functional expression of mutations in the human NaCl cotransporter: evidence for impaired routing mechanisms in Gitelman's syndrome. J Am Soc Nephrol 2002;13(6):1442-8.
CR  - 5.	Vargas-Poussou R, Dahan K, Kahila D, et al. Spectrum of mutations in Gitelman syndrome. J Am Soc Nephrol 2011;22(4):693-703.
CR  - 6.	Ea HK, Blanchard A, Dougados M, Roux C. Chondrocalcinosis secondary to hypomagnesemia in Gitelman's syndrome. J Rheumatol 2005;32(9):1840-2.
CR  - 7.	Berry MR, Robinson C, Karet Frankl FE. Unexpected clinical sequelae of Gitelman syndrome: hypertension in adulthood is common and females have higher potassium requirements. Nephrol Dial Transplant 2013;28(6):1533-42.
CR  - 8.	Stein JH. The pathogenetic spectrum of Bartter's syndrome. Kidney Int 1985;28(1):85-93.
CR  - 9.	Blanchard A, Vargas-Poussou R, Vallet M, et al. Indomethacin, amiloride, or eplerenone for treating hypokalemia in Gitelman syndrome. J Am Soc Nephrol 2015;26(2):468-75.
CR  - 10.	Calo LA, Marchini F, Davis PA, Rigotti P, Pagnin E, Semplicini A. Kidney transplant in Gitelman's syndrome. Report of the first case. J Nephrol 2003;16(1):144-7.
UR  - https://doi.org/10.17098/amj.461663
L1  - https://dergipark.org.tr/en/download/article-file/538793
ER  -