@article{article_463535, title={Increased mean platelet volume in patients with vestibular migraine}, journal={The European Research Journal}, volume={6}, pages={99–104}, year={2020}, DOI={10.18621/eurj.463535}, url={https://izlik.org/JA29WF32DU}, author={Çavuş, Mehmet Emin and Tanyeli, Talip Talha and Akcan, Fatih Alper and Bayır, Ömer and Gökkurt, Didem}, keywords={Hematologic parameters,mean platelet volume,neutrophil-to-lymphocyte ratio,platelet-to-lymphocyte ratio,vestibular migraine}, abstract={<p class="MsoNormal" style="text-align:justify;line-height:150%;"> <b> <span lang="en-us" style="font-size:18px;line-height:150%;font-family:’Times New Roman’, serif;" xml:lang="en-us">Objectives: </span> </b> <b> <span lang="en-us" style="font-size:18px;line-height:150%;font-family:’Times New Roman’, serif;" xml:lang="en-us"> </span> </b> <span style="font-size:12pt;line-height:150%;font-family:’Times New Roman’, serif;"> <span style="font-size:18px;">The purpose of this study was to investigate relation between mean platelet volume, platelet distribution width, platelet-to-lymphocyte ratio, neutrophil-to-lymphocyte ratio and vestibular migraine. </span> </span> </p> <p> </p> <p class="MsoNormal" style="text-align:justify;line-height:150%;"> <b> <span lang="en-us" style="font-size:18px;line-height:150%;font-family:’Times New Roman’, serif;" xml:lang="en-us">Methods: </span> </b> <span lang="en-us" style="font-size:18px;line-height:150%;font-family:’Times New Roman’, serif;" xml:lang="en-us"> </span> <span class="A1"> <span style="font-size:18px;line-height:150%;font-family:’Times New Roman’, serif;">This study was planned in prospective manner and </span> </span> <span style="font-size:18px;line-height:150%;font-family:’Times New Roman’, serif;">conducted in Ankara Polatlı State Hospital between April 2017 and May 2018. Thirty patients </span> <span class="A1"> <span style="font-size:18px;line-height:150%;font-family:’Times New Roman’, serif;">diagnosed with </span> </span> <span style="font-size:12pt;line-height:150%;font-family:’Times New Roman’, serif;"> <span style="font-size:18px;">vestibular migraine and thirty healthy, age and sex-matched subjects were enrolled to the study. Mean platelet volume, platelet distribution width, platelet count, neutrophil count and lymphocyte count in blood samples were measured. </span> </span> </p> <p> </p> <p class="MsoNormal" style="text-align:justify;line-height:150%;"> <b> <span lang="en-us" style="font-size:18px;line-height:150%;font-family:’Times New Roman’, serif;" xml:lang="en-us">Results: </span> </b> <span lang="en-us" style="font-size:18px;line-height:150%;font-family:’Times New Roman’, serif;" xml:lang="en-us"> </span> <span style="font-size:12pt;line-height:150%;font-family:’Times New Roman’, serif;"> <span style="font-size:18px;">The mean age of the patients with vestibular migraine was 39.90 ± 7.16 and t </span> <span style="font-size:18px;">he study group consisted of 11 males and 19 females. The </span> <span style="font-size:18px;">mean platelet volume and platelet distribution width </span> <span style="font-size:18px;"> values in patients with </span> <span style="font-size:18px;">vestibular migraine </span> <span style="font-size:18px;">were significantly higher than the control group ( </span> <i> <span style="font-size:18px;">p </span> </i> <span style="font-size:18px;"> < 0.001). There were no difference on mean neutrophil/lymphocyte ratio and platelet/lymphocyte ratio values between patient group and control group. </span> </span> </p> <p> </p> <p class="MsoNormal" style="margin-bottom:.0001pt;text-align:justify;line-height:150%;"> <span style="font-size:18px;"> </span> <span style="font-size:18px;"> </span> <span style="font-size:18px;"> </span> </p> <p class="MsoNormal" style="text-align:justify;line-height:150%;"> <b> <span lang="en-us" style="font-size:18px;line-height:150%;font-family:’Times New Roman’, serif;" xml:lang="en-us">Conclusions: </span> </b> <span lang="en-us" style="font-size:18px;line-height:150%;font-family:’Times New Roman’, serif;" xml:lang="en-us"> </span> <span style="font-size:18px;line-height:150%;font-family:’Times New Roman’, serif;">We found a positive relation of increased levels of m </span> <span style="font-size:12pt;line-height:150%;font-family:’Times New Roman’, serif;"> <span style="font-size:18px;">ean platelet volume and platelet distribution width </span> <span style="font-size:18px;"> with </span> <span style="font-size:18px;">vestibular migraine </span> <span style="font-size:18px;">. Higher m </span> <span style="font-size:18px;">ean platelet volume </span> <span style="font-size:18px;">is associated with atherosclerosis and thromboembolism. Vascular pathologies are blamed for both headache syndromes like migraine and vertiginous syndromes. This theory supports our study but pathophysiological mechanism is not clear.  </span> </span> </p> <p> </p> <p> </p>}, number={2}