
   @article{article_463906, title={Tiroglobulin Ölçümlerinin Düsük Titrelerdeki Anti-Tiroglobulinle İnterferansının Arastırılması}, journal={Medical Journal of Süleyman Demirel University}, volume={26}, pages={296–304}, year={2019}, DOI={10.17343/sdutfd.463906}, author={Çokluk, Erdem and Şekeroğlu, Ramazan and Bati, Bedia and Özturk, Mustafa}, keywords={İmmunometrik ölçüm,tiroglobulin,tiroglobulin antikor}, abstract={&amp;lt;p style="margin:0px;text-align:justify;line-height:200%;"&amp;gt; &amp;lt;b&amp;gt; &amp;lt;span style="margin:0px;line-height:200%;font-family:’Times New Roman’, serif;font-size:12pt;"&amp;gt;Sonuç: &amp;lt;/span&amp;gt; &amp;lt;/b&amp;gt; &amp;lt;span style="margin:0px;line-height:200%;font-family:’Times New Roman’, serif;font-size:12pt;"&amp;gt;
Bu çalı &amp;lt;/span&amp;gt; &amp;lt;span style="margin:0px;line-height:200%;font-family:’Times New Roman’, serif;font-size:12pt;"&amp;gt;ş &amp;lt;/span&amp;gt; &amp;lt;span style="margin:0px;line-height:200%;font-family:’Times New Roman’, serif;font-size:12pt;"&amp;gt;manın sonuçları TgAb mevcudiyetinin
dü &amp;lt;/span&amp;gt; &amp;lt;span style="margin:0px;line-height:200%;font-family:’Times New Roman’, serif;font-size:12pt;"&amp;gt;s &amp;lt;/span&amp;gt; &amp;lt;span style="margin:0px;line-height:200%;font-family:’Times New Roman’, serif;font-size:12pt;"&amp;gt;ük titrelerde bile Tg
ölçümlerini önemli oranda interfere etti &amp;lt;/span&amp;gt; &amp;lt;span style="margin:0px;line-height:200%;font-family:’Times New Roman’, serif;font-size:12pt;"&amp;gt;ğ &amp;lt;/span&amp;gt; &amp;lt;span style="margin:0px;line-height:200%;font-family:’Times New Roman’, serif;font-size:12pt;"&amp;gt;ini, dilüsyon oranın bu etkiyi de &amp;lt;/span&amp;gt; &amp;lt;span style="margin:0px;line-height:200%;font-family:’Times New Roman’, serif;font-size:12pt;"&amp;gt;ğ &amp;lt;/span&amp;gt; &amp;lt;span style="margin:0px;line-height:200%;font-family:’Times New Roman’, serif;font-size:12pt;"&amp;gt;i &amp;lt;/span&amp;gt; &amp;lt;span style="margin:0px;line-height:200%;font-family:’Times New Roman’, serif;font-size:12pt;"&amp;gt;ş &amp;lt;/span&amp;gt; &amp;lt;span style="margin:0px;line-height:200%;font-family:’Times New Roman’, serif;font-size:12pt;"&amp;gt;tirmedi &amp;lt;/span&amp;gt; &amp;lt;span style="margin:0px;line-height:200%;font-family:’Times New Roman’, serif;font-size:12pt;"&amp;gt;ğ &amp;lt;/span&amp;gt; &amp;lt;span style="margin:0px;line-height:200%;font-family:’Times New Roman’, serif;font-size:12pt;"&amp;gt;ini göstermektedir.
Ayrıca TgAb dı &amp;lt;/span&amp;gt; &amp;lt;span style="margin:0px;line-height:200%;font-family:’Times New Roman’, serif;font-size:12pt;"&amp;gt; &amp;lt;b&amp;gt;ş &amp;lt;/b&amp;gt; &amp;lt;/span&amp;gt; &amp;lt;span style="margin:0px;line-height:200%;font-family:’Times New Roman’, serif;font-size:12pt;"&amp;gt;ındaki
di &amp;lt;/span&amp;gt; &amp;lt;span style="margin:0px;line-height:200%;font-family:’Times New Roman’, serif;font-size:12pt;"&amp;gt;ğ &amp;lt;/span&amp;gt; &amp;lt;span style="margin:0px;line-height:200%;font-family:’Times New Roman’, serif;font-size:12pt;"&amp;gt;er otoimmun
antikorların Tg ölçümlerinde interferansa sebep olmadı &amp;lt;/span&amp;gt; &amp;lt;span style="margin:0px;line-height:200%;font-family:’Times New Roman’, serif;font-size:12pt;"&amp;gt;ğ &amp;lt;/span&amp;gt; &amp;lt;span style="margin:0px;line-height:200%;font-family:’Times New Roman’, serif;font-size:12pt;"&amp;gt;ı ya da çok az olabilece &amp;lt;/span&amp;gt; &amp;lt;span style="margin:0px;line-height:200%;font-family:’Times New Roman’, serif;font-size:12pt;"&amp;gt;ğ &amp;lt;/span&amp;gt; &amp;lt;span style="margin:0px;line-height:200%;font-family:’Times New Roman’, serif;font-size:12pt;"&amp;gt; &amp;lt;b&amp;gt;ini söyleyebiliriz. &amp;lt;/b&amp;gt; &amp;lt;/span&amp;gt; &amp;lt;/p&amp;gt; &amp;lt;p style="margin:0px;text-align:justify;line-height:200%;"&amp;gt; &amp;lt;b&amp;gt; &amp;lt;span style="margin:0px;line-height:200%;font-family:’Times New Roman’, serif;font-size:12pt;"&amp;gt;Bulgu: &amp;lt;/span&amp;gt; &amp;lt;/b&amp;gt; &amp;lt;span style="margin:0px;line-height:200%;font-family:’Times New Roman’, serif;font-size:12pt;"&amp;gt;TgAb
pozitif numunelerdeki recovery sonuçları % 21- % 56 oranında de &amp;lt;/span&amp;gt; &amp;lt;span style="margin:0px;line-height:200%;font-family:’Times New Roman’, serif;font-size:12pt;"&amp;gt;ğ &amp;lt;/span&amp;gt; &amp;lt;span style="margin:0px;line-height:200%;font-family:’Times New Roman’, serif;font-size:12pt;"&amp;gt;i &amp;lt;/span&amp;gt; &amp;lt;span style="margin:0px;line-height:200%;font-family:’Times New Roman’, serif;font-size:12pt;"&amp;gt;s &amp;lt;/span&amp;gt; &amp;lt;span style="margin:0px;line-height:200%;font-family:’Times New Roman’, serif;font-size:12pt;"&amp;gt; &amp;lt;b&amp;gt;irken, TgAb negatif
numunelerininki % 88 - % 96 arasında bulundu. &amp;lt;/b&amp;gt; &amp;lt;/span&amp;gt; &amp;lt;/p&amp;gt; &amp;lt;p style="margin:0px;text-align:justify;line-height:200%;"&amp;gt; &amp;lt;b&amp;gt; &amp;lt;span style="margin:0px;line-height:200%;font-family:’Times New Roman’, serif;font-size:12pt;"&amp;gt;Gereç-Yöntem: &amp;lt;/span&amp;gt; &amp;lt;/b&amp;gt; &amp;lt;span style="margin:0px;line-height:200%;font-family:’Times New Roman’, serif;font-size:12pt;"&amp;gt;
Bu amaçla dü &amp;lt;/span&amp;gt; &amp;lt;span style="margin:0px;line-height:200%;font-family:’Times New Roman’, serif;font-size:12pt;"&amp;gt;s &amp;lt;/span&amp;gt; &amp;lt;span style="margin:0px;line-height:200%;font-family:’Times New Roman’, serif;font-size:12pt;"&amp;gt;ük
ve yüksek TgAb konsantrasyonuna sahip serum havuzlarından alınan örnekler Tg
standartları içerisine ilave edilerek 1/2, 1/10 ve 1/20 dilüsyonla TgAb
konsantrasyonu 5, 10, 20, 40, 60, 80 ve 100 IU/ml olan numuneler hazırlandı.
Aynı sulandırma i &amp;lt;/span&amp;gt; &amp;lt;span style="margin:0px;line-height:200%;font-family:’Times New Roman’, serif;font-size:12pt;"&amp;gt;ş &amp;lt;/span&amp;gt; &amp;lt;span style="margin:0px;line-height:200%;font-family:’Times New Roman’, serif;font-size:12pt;"&amp;gt;lemi
TgAb negatif serum havuzları için de yapıldı ve örneklerde Tg ölçümleri
yapılarak geri kazanımlar (recovery) hesaplandı. &amp;lt;/span&amp;gt; &amp;lt;/p&amp;gt; &amp;lt;p style="margin:0px;text-align:justify;line-height:200%;"&amp;gt; &amp;lt;b&amp;gt; &amp;lt;span style="margin:0px;line-height:200%;font-family:’Times New Roman’, serif;font-size:12pt;"&amp;gt;Amaç: &amp;lt;/span&amp;gt; &amp;lt;/b&amp;gt; &amp;lt;span style="margin:0px;line-height:200%;font-family:’Times New Roman’, serif;font-size:12pt;"&amp;gt;
Tiroglobulin (Tg), tiroid follikülü için spesifik bir marker olarak kullanılır.
Ancak Tg ö}, number={3}, publisher={Süleyman Demirel University}