@article{article_467095, title={SYNAPTIC TRANSMISSION: A MODEL ON THE FORMATION OF END-PLATE POTENTIAL AND A STUDY ON SIMULATION}, journal={Communications Faculty of Sciences University of Ankara Series A2-A3 Physical Sciences and Engineering}, volume={61}, pages={24–32}, year={2019}, DOI={10.33769/aupse.467095}, author={Özbek, Levent and Temucın, Çağrı and Cengız, Bülent and Özturk, Fikri}, keywords={Synaptic transmission,EPP,MEPP}, abstract={<p class="MsoNormal" style="text-align:justify;line-height:150%;"> <span lang="en-us" style="font-size:8pt;line-height:150%;" xml:lang="en-us">In this study, the
emergences of postsynaptic action potentials are investigated using simulation
study which is depended on the statistical model of acetylcholine (Ach) quantal
release theory at motor end-plate. It is supposed that the end-plate potentials
(EPP) are sum of miniature end-plate potentials (MEPP) which are released as
quantal and random in number (N). By the hypothesis that N number has a Poisson
and MEPPs have a Gaussian distribution,  EPPs
are obtained by simulating distributions parameters. Our study suggests that
the simulation of the EPPs are  a
convenient tool  in understanding both
physiological process of synaptic transmission 
and pathological process of neuromuscular junction. </span> </p> <p> </p> <p class="MsoNormal" style="line-height:150%;"> <span lang="en-us" style="font-size:8pt;line-height:150%;" xml:lang="en-us"> </span> </p> <p>  </p>}, number={1}, publisher={Ankara University}