@article{article_485447, title={CHANGES IN CERTAIN ACUTE PHASE PROTEINS OF COMMON CARP (Cyprinus carpio) EXPOSED TO ORGANOPHOSPHATE INSECTICIDES}, journal={Aquatic Research}, volume={2}, pages={16–23}, year={2019}, DOI={10.3153/AR19002}, author={Zapryanova, Dimitrinka and Atanasoff, Alexander and Sımeonov, Radoslav and Ürkü, Çiğdem and Nıcolov, Galin and Georgıeva, Teodor}, keywords={Acute phase proteins,Albumin,Ceruloplasmin,Common carp,Fibrinogen}, abstract={<p class="MsoNormal" style="margin-top:0cm;margin-right:21.85pt;margin-bottom:.0001pt;margin-left:21.3pt;text-align:justify;"> <span lang="en-us" style="font-size:10pt;" xml:lang="en-us">The acute phase response (APR) is a nonspecific reaction of fish to
disturbances in homeostasis. The aim of present study was to investigate
quantitative changes that occur in the concentration of acute phase proteins
(APPs) in the blood of </span> <span style="font-size:10pt;">commercial size </span> <span lang="en-us" style="font-size:10pt;" xml:lang="en-us">common carp ( <i>Cyprinus carpio L. </i>) exposed to </span> <span style="font-size:10pt;">organophosphate insecticides </span> <span style="font-size:10pt;"> </span> <span style="font-size:10pt;">within the month of </span> <span lang="en-us" style="font-size:10pt;" xml:lang="en-us">April during ameliorative
activities. </span> <span lang="en-us" style="font-size:10pt;" xml:lang="en-us"> </span> <span lang="en-us" style="font-size:10pt;" xml:lang="en-us">Parameters examined
were fibrinogen (Fib), ceruloplasmin (Cp) as a positive APPs and albumin (Alb)
as a negative APP. Histological sections of the hepatopancreas and kidneys from
25 fish have been examined. The hepatopancreas was chosen for this
investigation as it is the primary site of acute phase protein synthesis. APP
parameters plasma </span> <span lang="en-gb" style="font-size:10pt;" xml:lang="en-gb">fibrinogen ( <i>P </i><0.05)
registered a significantly increased and albumin ( <i>P </i><0.05) exhibited statistically
declined in treated group. </span> <span lang="en-gb" style="font-size:10pt;" xml:lang="en-gb"> </span> <span lang="en-gb" style="font-size:10pt;" xml:lang="en-gb">Based on the data acquired in this study, it was
concluded that, the carp do not exhibit a strong APP synthesis during the early
stages of an APR after spraying with organophosphate insecticides. </span> <span style="font-size:10pt;"> The results from this study </span> <span lang="en-us" style="font-size:10pt;" xml:lang="en-us"> show that t </span> <span lang="en-gb" style="font-size:10pt;" xml:lang="en-gb">he concentrations of fibrinogen are not significantly increase as well as
the levels of ceruloplasmin remained unchanged. </span> </p> <p> </p>}, number={1}, publisher={Nuray ERKAN ÖZDEN}