TY  - JOUR
T1  - Propolis from Romania and Turkey: Comparative Antioxidant and Antibacterial Activity
AU  - Bobıs, Otilia
AU  - Keskın, Merve
AU  - Keskın, Saban
AU  - Kolaylı, Sevgi
AU  - Nıculae, Mihaela
AU  - Urcan, Adriana
AU  - Pasca, Claudia
AU  - Mărghıtas, Liviu Al.
AU  - Dezmırean, Daniel S.
PY  - 2018
DA  - December
JF  - Journal of Apitherapy and Nature
JO  - J.Apit.Nat.
PB  - Oktay YILDIZ
WT  - DergiPark
SN  - 2667-4734
SP  - 38
EP  - 38
VL  - 1
IS  - 3
LA  - en
AB  - Propolis is an importantbee product, used by the bees to seal the cracks and to hygiene the wax combsafter brood rearing (Huang et al., 2014). The bioactive compounds of propolisoriginate from plant resins that bees collect, mix with own secretions and wax.Propolis chemical composition is different according to the geographicallocation (Mărghitaş et al., 2013), botanical origin and bee specie (Silici andKutluca, 2005). The aim of the study was to determine the chemical compositionof different propolis samples from Romania and Turkey and to correlate thecomposition with the antioxidant and antibacterial activity of tincturesagainst Gram-positive and Gram-negative bacteria. Soxhlet extraction,gravimetric measurements, spectrophotometric and chromatographic determinationswere used in the study. The antimicrobial properties were evaluated in vitro towards both reference andclinical strains of Staphylococcus aureus,Salmonella enteritis, Salmonella typhimurium, Escherichia coli and Pseudomonas aeruginosa using the discdiffusion assay; the minimum inhibitory (MIC) and minimum bactericidal (MBC)concentrations were established by a broth microdilution method and used tocalculate the bactericidal index for each extract.  The wax content of the samples ranged withinthe limits provided by the Argentinian and European standards in effect. Balsamcontent of the samples was above 30%, providing a tincture with highantioxidant properties. High amounts of total polyphenols and flavonoids weredetermined in all samples, though different for Romanian and Turkish samples.The inhibitory ability was different for samples coming from differentgeographical origins, depending fundamentally on plant source resins, but alsoon bacterial species.  
KW  - bee product
KW  - propolis
KW  - Antioxidant activity
CR  - 1 Marghitas LA, Dezmirean DS, Bobis O (2013) Important developments in Romanian propolis research. Evidence-Based Complementary and Alternative Medicine 2013: 159392.
CR  - 2 Huang MI, Zhang C-P, Wang K, Li GQ, Hu FL (2014) Recent advances in the chemical composition of propolis. Molecules 19: 19610-19632.
CR  - 3 Silici S, Kutluca S (2005) Chemical composition and antibacterial activity of propolis collected by three different races of honeybees in the same region. Journal of Ethnopharmacology 99: 69-73.
UR  - https://dergipark.org.tr/en/pub/jan/issue//489289
L1  - https://dergipark.org.tr/en/download/article-file/583793
ER  -