TY  - JOUR
T1  - Effect of Brazilian Propolis-containing Ointment on Genital Itching in Menopausal Women
AU  - Mıura, Hiroshi
AU  - Mıura, Yasuko
AU  - Shımoda, Yuki
AU  - Kagabu, Satoko
AU  - Tsubakı, Hiromitsu
AU  - Terada, Yukihiro
PY  - 2018
DA  - December
JF  - Journal of Apitherapy and Nature
JO  - J.Apit.Nat.
PB  - Oktay YILDIZ
WT  - DergiPark
SN  - 2667-4734
SP  - 79
EP  - 79
VL  - 1
IS  - 3
LA  - en
AB  - Introduction:Menopausal women can develop genital pruritus due to skin contraction anddrying associated with estrogen deficiency. The causes of pruritus includecontact dermatitis, fungal dermatitis, dry dermatitis, and others. A definitecause often cannot be identified. Propolis has reported antibacterial,antifungal, and antipruritic effects, and can inhibit histamine release.Accordingly, application of a propolis-containing agent to the genital regionin menopausal women may treat many causes of pruritus.Methods:Postmenopausal women with genital pruritus were randomly divided into 3treatment groups: Group A (n=9) was treated with a 1% Brazilianpropolis-containing ointment, Group B (n=6) with an antihistamine-containingointment, and Group C (control, n=5) with a Vaseline ointment. Each groupapplied ointment to the vulva twice a day. After 14 days, improvement inpruritus was quantified with the visual analog scale (VAS). The study protocolwas approved by the ethics committee of Akita University.Results: Theaverage VAS score was 4.7 for Group A, 3.0 for Group B, and 9.5 for Group C.There was a significant difference between Group C and the other 2 groups.Conclusion: The 1%Brazilian propolis-containing ointment may be not as effective as the antihistamineointment, but did have some antipruritic effect. Acknowledgements: This research was supportedby Yamada Research Grant
KW  - Propolis
KW  - Menopausal Women
KW  - Postmenopausal
CR  - .
UR  - https://dergipark.org.tr/en/pub/jan/issue//489992
L1  - https://dergipark.org.tr/en/download/article-file/584901
ER  -